Invention Application
- Patent Title: RECOMBINANT PICHIA PASTORIS CELL
- Patent Title (中): 重组PICHIA PASTORIS细胞
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Application No.: PCT/AT2008000433Application Date: 2008-12-05
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Publication No.: WO2009070822A2Publication Date: 2009-06-11
- Inventor: JANESCH BETTINA , GLIEDER ANTON , HARTNER FRANZ , SCHROER KIRSTEN , LUEF KLAUS PETER , PSCHEIDT BEATE
- Applicant: ANGEWANDTE BIOKATALYSE KOMPETE , UNIV GRAZ TECH , JANESCH BETTINA , GLIEDER ANTON , HARTNER FRANZ , SCHROER KIRSTEN , LUEF KLAUS PETER , PSCHEIDT BEATE
- Assignee: ANGEWANDTE BIOKATALYSE KOMPETE,UNIV GRAZ TECH,JANESCH BETTINA,GLIEDER ANTON,HARTNER FRANZ,SCHROER KIRSTEN,LUEF KLAUS PETER,PSCHEIDT BEATE
- Current Assignee: ANGEWANDTE BIOKATALYSE KOMPETE,UNIV GRAZ TECH,JANESCH BETTINA,GLIEDER ANTON,HARTNER FRANZ,SCHROER KIRSTEN,LUEF KLAUS PETER,PSCHEIDT BEATE
- Priority: AT19832007 2007-12-05
- Main IPC: C12N15/63
- IPC: C12N15/63 ; C12N9/02 ; C12N9/04 ; C12N9/10 ; C12P7/16 ; C12R1/84
Abstract:
The present invention relates to a recombinant Pichia pastoris cell comprising at least one mutation in the dihydroxyacetone synthase gene 2 (DAS2) resulting in a reduced dihydroxyacetone synthase activity compared to a wild-type Pichia pastoris cell, wherein the DAS2 gene comprises a nucleotide sequence having at least 80% identity with SEQ ID No. 1.
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