Invention Application
- Patent Title: IGF-II/GF-IIE BINDING PROTEINS
- Patent Title (中): IGF-II / GF-IIE结合蛋白
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Application No.: PCT/US2009043273Application Date: 2009-05-08
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Publication No.: WO2009137758A3Publication Date: 2010-03-18
- Inventor: DRANSFIELD DANIEL , COHEN EDWARD , ADAMS TIMOTHY , COSGROVE LEAH
- Applicant: DYAX CORP , COMMW SCIENT IND RES ORG , DRANSFIELD DANIEL , COHEN EDWARD , ADAMS TIMOTHY , COSGROVE LEAH
- Assignee: DYAX CORP,COMMW SCIENT IND RES ORG,DRANSFIELD DANIEL,COHEN EDWARD,ADAMS TIMOTHY,COSGROVE LEAH
- Current Assignee: DYAX CORP,COMMW SCIENT IND RES ORG,DRANSFIELD DANIEL,COHEN EDWARD,ADAMS TIMOTHY,COSGROVE LEAH
- Priority: US5342708 2008-05-15; US16318009 2009-03-25; US5195608 2008-05-09
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/00 ; C12P21/08
Abstract:
Proteins that bind to IGF-II and/or IGF-IIE and methods of using such proteins are described. Also disclosed are new methods for treatment of cancer. Cancer is treated by administration of an IGF-II/IGF-IIE binding protein and an additional therapy such as a growth hormone/growth hormone releasing hormone pathway modulator or epidermal growth factor receptor inhibitor.
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