The present invention relates to a production method for an epoxy substrate exhibiting a nanopattern, comprising the stages of: (a) forming a titanium oxide film by anodization of a titanium substrate; (b) obtaining a titanium substrate having a concave shape formed on its surface by removing the titanium oxide film from the titanium substrate on which the titanium oxide film has been formed; (c) coating an epoxy resin onto the titanium substrate on which the concave shape has been formed; and (d) obtaining an epoxy substrate formed with a nanopattern of convex surfaces by removing the titanium substrate. In the production method of the present invention, an epoxy substrate formed with a nanopattern of convex surfaces is produced after anodizing titanium, coating an epoxy resin onto a nanopattern formed with a concave shape on the titanium surface, and removing the titanium substrate. This straightforward process makes it possible to efficiently produce an epoxy resin exhibiting a nanopattern for the measurement of blood coagulation formed with a fine pattern which is uniform and on the nano scale. Further, the epoxy substrate produced by means of the present invention makes it possible to efficiently use an electrochemical technique to ascertain whether or not blood coagulation is present in a blood sample.