Invention Application
WO2010001186A4 COMBINATION OF A PARP INHIBITOR AND AN AKT KINASE ACTIVATING COMPOUND
审中-公开
PARP抑制剂与AKT激酶活化化合物的组合
- Patent Title: COMBINATION OF A PARP INHIBITOR AND AN AKT KINASE ACTIVATING COMPOUND
- Patent Title (中): PARP抑制剂与AKT激酶活化化合物的组合
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Application No.: PCT/HU2009000055Application Date: 2009-07-01
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Publication No.: WO2010001186A4Publication Date: 2010-03-11
- Inventor: GALLYAS FERENC , SUEMEGI BALAZS , VETOE SARA , ACS PETER , KOMOLY SAMUEL , ILLES ZSOLT
- Applicant: PECSI TUDOMANYEGYETEM , GALLYAS FERENC , SUEMEGI BALAZS , VETOE SARA , ACS PETER , KOMOLY SAMUEL , ILLES ZSOLT
- Assignee: PECSI TUDOMANYEGYETEM,GALLYAS FERENC,SUEMEGI BALAZS,VETOE SARA,ACS PETER,KOMOLY SAMUEL,ILLES ZSOLT
- Current Assignee: PECSI TUDOMANYEGYETEM,GALLYAS FERENC,SUEMEGI BALAZS,VETOE SARA,ACS PETER,KOMOLY SAMUEL,ILLES ZSOLT
- Priority: HU0800414 2008-07-04
- Main IPC: A61K45/06
- IPC: A61K45/06
Abstract:
The primary subject of the invention is the use of a PARP inhibitor and an Akt kinase activating compound in combination in the treatment of pathological conditions related to PARP activation and/or that could benefit from Akt activation. A further subject of the invention is the use of a PARP inhibitor and an Akt kinase activating compound in combination for the preparation of pharmaceutical composition or kit for the treatment of a pathological condition related to PARP activation. The invention also relates to pharmaceutical composition, which contains a PARP-inhibitor and an Akt kinase activating compound together with auxiliaries generally used in pharmacy.
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