Invention Application
WO2010048526A3 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
审中-公开
CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR的调节剂
- Patent Title: MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
- Patent Title (中): CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR的调节剂
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Application No.: PCT/US2009061882Application Date: 2009-10-23
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Publication No.: WO2010048526A3Publication Date: 2010-09-16
- Inventor: BINCH HAYLEY , FANNING LEV T D , HURLEY DENNIS , SHETH URVI , SILINA ALINA , YANG XIAOQING , BOTFIELD MARTYN , GROOTENHUIS PETER D J , VAN GOOR FREDRICK , NUMA MEHDI MICHEL DJAMEL
- Applicant: VERTEX PHARMA , BINCH HAYLEY , FANNING LEV T D , HURLEY DENNIS , SHETH URVI , SILINA ALINA , YANG XIAOQING , BOTFIELD MARTYN , GROOTENHUIS PETER D J , VAN GOOR FREDRICK , NUMA MEHDI MICHEL DJAMEL
- Assignee: VERTEX PHARMA,BINCH HAYLEY,FANNING LEV T D,HURLEY DENNIS,SHETH URVI,SILINA ALINA,YANG XIAOQING,BOTFIELD MARTYN,GROOTENHUIS PETER D J,VAN GOOR FREDRICK,NUMA MEHDI MICHEL DJAMEL
- Current Assignee: VERTEX PHARMA,BINCH HAYLEY,FANNING LEV T D,HURLEY DENNIS,SHETH URVI,SILINA ALINA,YANG XIAOQING,BOTFIELD MARTYN,GROOTENHUIS PETER D J,VAN GOOR FREDRICK,NUMA MEHDI MICHEL DJAMEL
- Priority: US10783008 2008-10-23
- Main IPC: C07D451/02
- IPC: C07D451/02 ; A61K31/439 ; A61P11/00
Abstract:
The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR. (l); or pharmaceutically acceptable salts thereof, wherein: ring A is selected from:
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