Invention Application
- Patent Title: CYCLIN DEPENDENT KINASE INHIBITORS AND METHODS OF USE
- Patent Title (中): CYCLIN依赖性激酶抑制剂及其使用方法
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Application No.: PCT/US2010034816Application Date: 2010-05-13
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Publication No.: WO2010132725A3Publication Date: 2011-03-31
- Inventor: SHARPLESS NORMAN E , ROBERTS PATRICK J , WONG KWOK , LIU YAN , JOHNSON SOREN
- Applicant: UNIV NORTH CAROLINA , SHARPLESS NORMAN E , ROBERTS PATRICK J , WONG KWOK , LIU YAN , JOHNSON SOREN
- Assignee: UNIV NORTH CAROLINA,SHARPLESS NORMAN E,ROBERTS PATRICK J,WONG KWOK,LIU YAN,JOHNSON SOREN
- Current Assignee: UNIV NORTH CAROLINA,SHARPLESS NORMAN E,ROBERTS PATRICK J,WONG KWOK,LIU YAN,JOHNSON SOREN
- Priority: US17772409 2009-05-13
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61K38/17 ; A61K38/20 ; A61P1/00 ; A61P37/00 ; A61P37/08
Abstract:
The presently disclosed subject matter relates to methods and compositions for protecting healthy cells from damage due to DNA damaging agents. In particular, the presently disclosed subject matter relates to the protective action of selective cyclin dependent kinase 4/6 (CDK4/6) inhibitors administered to subjects that have been exposed to or that are at risk of exposure to DNA damage.
Information query
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