Invention Application
- Patent Title: MODIFIED AAV CAPSID POLYPEPTIDES
- Patent Title (中): 改良AAV CAPSID多糖
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Application No.: PCT/EP2010057370Application Date: 2010-05-28
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Publication No.: WO2010136549A3Publication Date: 2011-02-17
- Inventor: MUELLER OLIVER , KATUS HUGO , VARADI KARL , KLEINSCHMIDT JUERGEN
- Applicant: DEUTSCHES KREBSFORSCH , UNIV RUPRECHT KARLS HEIDELBERG , MUELLER OLIVER , KATUS HUGO , VARADI KARL , KLEINSCHMIDT JUERGEN
- Assignee: DEUTSCHES KREBSFORSCH,UNIV RUPRECHT KARLS HEIDELBERG,MUELLER OLIVER,KATUS HUGO,VARADI KARL,KLEINSCHMIDT JUERGEN
- Current Assignee: DEUTSCHES KREBSFORSCH,UNIV RUPRECHT KARLS HEIDELBERG,MUELLER OLIVER,KATUS HUGO,VARADI KARL,KLEINSCHMIDT JUERGEN
- Priority: EP09161375 2009-05-28
- Main IPC: C12N15/864
- IPC: C12N15/864
Abstract:
The present invention is concerned with the provision of a polynucleotide encoding an AAV capsid polypeptide comprising an inserted peptide and a vector comprising said polynucleotide. Moreover, contemplated is a host cell comprising said polynucleotide or vector, a method for the manufacture of said capsid polypeptide as well as said polypeptide. Further included is an antibody specifically binding to said polypeptide and a medicament comprising said polynucleotide, vector, polypeptide, or antibody. Also contemplated are the use of said polynucleotide, vector, polypeptide, or antibody for the manufacture of a medicament for the treatment of vascular disease and a method for the identification of a compound binding to said polypeptide.
Information query
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