Invention Application
- Patent Title: PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF
- Patent Title (中): 磷酸二酯酶抑制剂及其用途
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Application No.: PCT/NZ2012/000053Application Date: 2012-04-16
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Publication No.: WO2012150866A1Publication Date: 2012-11-08
- Inventor: CLINCH, Keith , CRUMP, Douglas Ronald , EVANS, Gary Brian , HAZLETON, Keith Zachary , MASON, Jennifer Mary , SCHRAMM, Vern L. , TYLER, Peter Charles
- Applicant: INDUSTRIAL RESEARCH LIMITED , ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY , CLINCH, Keith , CRUMP, Douglas Ronald , EVANS, Gary Brian , HAZLETON, Keith Zachary , MASON, Jennifer Mary , SCHRAMM, Vern L. , TYLER, Peter Charles
- Applicant Address: Gracefield Research Centre 69 Gracefield Road Lower Hutt 5010 NZ
- Assignee: INDUSTRIAL RESEARCH LIMITED,ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY,CLINCH, Keith,CRUMP, Douglas Ronald,EVANS, Gary Brian,HAZLETON, Keith Zachary,MASON, Jennifer Mary,SCHRAMM, Vern L.,TYLER, Peter Charles
- Current Assignee: INDUSTRIAL RESEARCH LIMITED,ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY,CLINCH, Keith,CRUMP, Douglas Ronald,EVANS, Gary Brian,HAZLETON, Keith Zachary,MASON, Jennifer Mary,SCHRAMM, Vern L.,TYLER, Peter Charles
- Current Assignee Address: Gracefield Research Centre 69 Gracefield Road Lower Hutt 5010 NZ
- Agency: BALDWINS INTELLECTUAL PROPERTY
- Priority: US61/481,784 20110503
- Main IPC: C07F9/6561
- IPC: C07F9/6561 ; C07D487/04 ; A61K31/675 ; A61P33/06
Abstract:
The invention relates to compounds of formula (I) that are inhibitors of hypoxanthine and/or guanine purine phosphoribosyltransferases and to pharmaceutical compositions containing the compounds, processes for preparing the compounds, and methods of treating diseases or conditions in which it is desirable to inhibit hypoxanthine and/or guanine purine phosphoribosyltransferases. Such diseases include malaria.
Information query
