发明申请
- 专利标题： LIPHAGAL ENANTIOMERS AND THEIR DERIVATIVES AND PRECURSORS, AND ENANTIOSELECTIVE METHODS OF MAKING THE SAME
- 专利标题（中）： 脂肪成分及其衍生物和前体，以及其制备方法
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申请号： PCT/US2012/040310申请日： 2012-05-31
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公开(公告)号： WO2012166987A2公开(公告)日： 2012-12-06
- 发明人: STOLTZ, Brian, M. , MCFADDEN, Ryan , VIRGIL, Scott, C. , KOLDING, Helene , ALLEVA, Jennifer, L. , DAY, Joshua, J.
- 申请人： CALIFORNIA INSTITUTE TECHNOLOGY , STOLTZ, Brian, M. , MCFADDEN, Ryan , VIRGIL, Scott, C. , KOLDING, Helene , ALLEVA, Jennifer, L. , DAY, Joshua, J.
- 申请人地址： 1200 East California Boulevard, M/D 210-85 Pasadena, CA 91125 US
- 专利权人： CALIFORNIA INSTITUTE TECHNOLOGY,STOLTZ, Brian, M.,MCFADDEN, Ryan,VIRGIL, Scott, C.,KOLDING, Helene,ALLEVA, Jennifer, L.,DAY, Joshua, J.
- 当前专利权人： CALIFORNIA INSTITUTE TECHNOLOGY,STOLTZ, Brian, M.,MCFADDEN, Ryan,VIRGIL, Scott, C.,KOLDING, Helene,ALLEVA, Jennifer, L.,DAY, Joshua, J.
- 当前专利权人地址： 1200 East California Boulevard, M/D 210-85 Pasadena, CA 91125 US
- 代理机构： SCHNEIDER, Lauren, E.
- 优先权： US61/491,631 20110531
- 主分类号： A61K31/343
- IPC分类号： A61K31/343 ; A61K31/34 ; C07D307/77 ; A61P35/00
摘要：
Enantioenriched compositions of liphagal and its derivatives and precursors include more than 50 mol% of a first enantiomer based on the total amount of a first and a second enantiomer. A method of making an enantioenriched composition includes catalytic enantioselective alkylation, ring expansion, and intramolecular aryne cylization.
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