发明申请
WO2013087090A1 TREATMENT OF TINNITUS THROUGH MODULATION OF CHLORIDE CO-TRANSPORTER NKCC1 IN THE AUDITORY SYSTEM
审中-公开
在审核系统中通过调节氯化钴共转运剂NKCC1处理荨麻疹
- 专利标题： TREATMENT OF TINNITUS THROUGH MODULATION OF CHLORIDE CO-TRANSPORTER NKCC1 IN THE AUDITORY SYSTEM
- 专利标题（中）： 在审核系统中通过调节氯化钴共转运剂NKCC1处理荨麻疹
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申请号： PCT/EP2011/072480申请日： 2011-12-12
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公开(公告)号： WO2013087090A1公开(公告)日： 2013-06-20
- 发明人: KNIPPER, Marlies , RUETTIGER, Lukas
- 申请人： AURIS MEDICAL AG , KNIPPER, Marlies , RUETTIGER, Lukas
- 申请人地址： Aeschenvorstadt 37 CH - 4051 Basel CH
- 专利权人： AURIS MEDICAL AG,KNIPPER, Marlies,RUETTIGER, Lukas
- 当前专利权人： AURIS MEDICAL AG,KNIPPER, Marlies,RUETTIGER, Lukas
- 当前专利权人地址： Aeschenvorstadt 37 CH - 4051 Basel CH
- 代理机构： GRAF VON STOSCH, Andreas
- 主分类号： A61K31/00
- IPC分类号： A61K31/00 ; A61K31/195 ; A61K31/40 ; A61K31/404 ; A61K31/425 ; A61K31/549 ; A61K31/635 ; A61K31/64 ; A61P27/16
摘要：
The present invention relates to the treatment or prevention of tinnitus. More precisely, the present invention relates to a compound modulating chloride co-transporter NKCC1 (chloride co-transporter modulator) for use in the treatment of tinnitus. In addition, the present invention concerns pharmaceutical compositions comprising such an NKCC1 chloride co-transporter modulator as an active agent, a method for the treatment or prevention of tinnitus by administering such a chloride co-transporter modulator, and a screening method for the identification and characterization of compounds capable of modulating chloride co-transporter NKCC1.
