Invention Application
WO2014058188A1 COMBINATION DRUG COMPRISING GEMIGLIPTIN AND METFORMIN, AND METHOD FOR THE PREPARATION THEREOF
审中-公开
包含GEMIGLIPTIN和METFORMIN的组合药物及其制备方法
- Patent Title: COMBINATION DRUG COMPRISING GEMIGLIPTIN AND METFORMIN, AND METHOD FOR THE PREPARATION THEREOF
- Patent Title (中): 包含GEMIGLIPTIN和METFORMIN的组合药物及其制备方法
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Application No.: PCT/KR2013/008932Application Date: 2013-10-07
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Publication No.: WO2014058188A1Publication Date: 2014-04-17
- Inventor: KIM, Geun Tae , YUN, Duck Il , PARK, Ki Sook
- Applicant: LG LIFE SCIENCES LTD.
- Applicant Address: LG Gwanghwamun Bldg. 58, Saemunan-ro (Sinmunno 2-ga) Jongno-gu Seoul 110-783 KR
- Assignee: LG LIFE SCIENCES LTD.
- Current Assignee: LG LIFE SCIENCES LTD.
- Current Assignee Address: LG Gwanghwamun Bldg. 58, Saemunan-ro (Sinmunno 2-ga) Jongno-gu Seoul 110-783 KR
- Agency: CHOI, Kyu Pal
- Priority: KR10-2012-0111404 20121008
- Main IPC: A61K9/24
- IPC: A61K9/24 ; A61K9/20 ; A61K31/155
Abstract:
The present invention relates to a combination drug comprising gemigliptin and metformin as active components and a method for the preparation thereof. The pharmaceutical composition consisting of a first layer comprising metformin and a second layer comprising gemigliptin according to the present invention has a superior effect on the prevention and treatment of diabetes and their complex diseases, and reduces the adverse effects of each component. In addition, the present composition comprises gemigliptin and metformin in a separated form so as to maintain the inherent dissolution rates of both components and improve patient compliance.
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