发明申请
- 专利标题: METHODS OF DIAGNOSING AND TREATING CHRONIC PAIN
- 专利标题(中): 诊断和治疗慢性疼痛的方法
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申请号: PCT/US2014/033830申请日: 2014-04-11
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公开(公告)号: WO2014169226A2公开(公告)日: 2014-10-16
- 发明人: AJIT, Seena , SACAN, Ahmet , ALEXANDER, Guillermo , SCHWARTZMAN, Robert, J. , MCDONALD, Marguerite
- 申请人: PHILADELPHIA HEALTH & EDUCATION CORPORATION D/B/A DREXEL UNIVERSITY OF MEDICINE , DREXEL UNIVERSITY
- 申请人地址: 245 N. 15th Street Philadelphia, PA 19104 US
- 专利权人: PHILADELPHIA HEALTH & EDUCATION CORPORATION D/B/A DREXEL UNIVERSITY OF MEDICINE,DREXEL UNIVERSITY
- 当前专利权人: PHILADELPHIA HEALTH & EDUCATION CORPORATION D/B/A DREXEL UNIVERSITY OF MEDICINE,DREXEL UNIVERSITY
- 当前专利权人地址: 245 N. 15th Street Philadelphia, PA 19104 US
- 代理机构: CHIANG, Elbert, C. et al.
- 优先权: US61/811,256 20130412; US61/811,374 20130412; US61/886,142 20131003
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
The invention includes compositions and methods useful for the diagnosis, prognosis, treatment, assessment, and characterization of inflammation or pain (e.g., neuropathic pain) in a subject in need thereof, based upon the expression level of at least one miRNA that is associated with inflammation or pain. In one aspect, the invention relates to compositions and methods for the prediction of a subject's responsiveness of a treatment of inflammation or pain.