Invention Application
- Patent Title: COMBINATION of PI3K-INHIBITORS
- Patent Title (中): PI3K抑制剂的组合
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Application No.: PCT/EP2014/075886Application Date: 2014-11-28
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Publication No.: WO2015082322A1Publication Date: 2015-06-11
- Inventor: LIU, Ningshu
- Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
- Applicant Address: Müllerstr. 178 13353 Berlin DE
- Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
- Current Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
- Current Assignee Address: Müllerstr. 178 13353 Berlin DE
- Agency: BIP PATENTS
- Priority: EP13195485.1 20131203
- Main IPC: A61K45/06
- IPC: A61K45/06 ; A61K31/519 ; A61K31/5377 ; A61K33/14 ; A61P35/00 ; A61P35/04 ; A61K51/02
Abstract:
The present invention relates to combinations of at least two components, component A and component B, component A being an inhibitor of PI3K kinase, and component B being radium 223, particularly a pharmaceutically acceptable salt of radium-223. Another aspect of the present invention relates to the use of such combinations as described herein for the preparation of a medicament for the treatment or prophylaxis of a disease, particurlarly for the treatment of breast and prostate cancer as well as their bone metatases.
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