发明申请
- 专利标题： PROPELLANE DERIVATES AND SYNTHESIS
- 专利标题（中）： 推进剂衍生物和合成
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申请号： PCT/US2015/018886申请日： 2015-03-05
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公开(公告)号： WO2015134710A1公开(公告)日： 2015-09-11
- 发明人: BUNKER, Kevin, Duane
- 申请人： KALYRA PHARMACEUTICALS, INC.
- 申请人地址： 6181 Cornerstone Court, Suite 106 San Diego, CA 92121 US
- 专利权人： KALYRA PHARMACEUTICALS, INC.
- 当前专利权人： KALYRA PHARMACEUTICALS, INC.
- 当前专利权人地址： 6181 Cornerstone Court, Suite 106 San Diego, CA 92121 US
- 代理机构： MILLER, Kimberly, J.
- 优先权： US61/949,733 20140307
- 主分类号： C07C61/125
- IPC分类号： C07C61/125 ; C07C235/26 ; C07C211/19
摘要：
Disclosed herein are compounds of the general Formula (I), and methods of synthesizing substituted bicyclo[1.1.1 jpentanes. The synthetic methods described herein use a [1.1.1]propellane, a Group VIII transition metal compound, a hydride source and a reagent that can contribute a substituent to form a substituted bicycIo[1.1.1 ]pentane, such as a compound of the general Formula (I).
