Invention Application
- Patent Title: METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS
- Patent Title (中): 生物化学化合物的方法，试剂和细胞
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Application No.: PCT/US2015/036050Application Date: 2015-06-16
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Publication No.: WO2015195678A1Publication Date: 2015-12-23
- Inventor: BOTES, Adriana Leonora , CONRADIE, Alex Van Eck , HADDOUCHE, Ramdane
- Applicant: INVISTA Technologies S.à r.l.
- Applicant Address: Zweigniederlassung St. Gallen Kreuzackerstrasse 9 9000 St. Gallen CH
- Assignee: INVISTA Technologies S.à r.l.
- Current Assignee: INVISTA Technologies S.à r.l.
- Current Assignee Address: Zweigniederlassung St. Gallen Kreuzackerstrasse 9 9000 St. Gallen CH
- Agency: LODOVICE, Ian J. et al.
- Priority: US62/012,659 20140616; US62/012,604 20140616; US62/012,666 20140616
- Main IPC: C12P7/42
- IPC: C12P7/42
Abstract:
This document describes biochemical pathways for producing 7-hydroxyheptanoate methyl ester and heptanoic acid heptyl ester using one or more of a fatty acid O-methyltransferase , an alcohol O-acetyltransferase , and a monooxygenase , as well as recombinant hosts expressing one or more of such exogenous enzymes. 7-hydroxyheptanoate methyl esters and heptanoic acid heptyl esters can be enzymatically converted to pimelic acid, 7-aminoheptanoate, 7-hydroxyheptanoate, heptamethylenediamine, or 1,7-heptanediol.
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