Invention Application
- Patent Title: NANOTUBE TRANS-MEMBRANE CHANNELS MIMICKING BIOLOGICAL PORINS
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Application No.: PCT/US2015/054084Application Date: 2015-10-05
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Publication No.: WO2016057427A1Publication Date: 2016-04-14
- Inventor: GENG, Jia , ZHANG, Jianfei , FROLOV, Vadim , NOY, Aleksandr
- Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , UNIVERSIDAD DEL PAÍS VASCO , GENG, Jia , ZHANG, Jianfei , FROLOV, Vadim
- Applicant Address: 2300 First Street, Suite 204 Livermore, California 94550 US
- Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC,THE REGENTS OF THE UNIVERSITY OF CALIFORNIA,UNIVERSIDAD DEL PAÍS VASCO,GENG, Jia,ZHANG, Jianfei,FROLOV, Vadim
- Current Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC,THE REGENTS OF THE UNIVERSITY OF CALIFORNIA,UNIVERSIDAD DEL PAÍS VASCO,GENG, Jia,ZHANG, Jianfei,FROLOV, Vadim
- Current Assignee Address: 2300 First Street, Suite 204 Livermore, California 94550 US
- Agency: KONSKI, Antoinette F. et al.
- Priority: US62/060,494 20141006
- Main IPC: C01B31/02
- IPC: C01B31/02 ; C01B21/064 ; C01G39/06 ; A61K47/48 ; A61K51/02 ; C12Q1/68
Abstract:
Provided herein is a nanopore structure, which in one aspect is a "carbon nanotube porin", that comprises a short nanotube with an associated lipid coating. Also disclosed are compositions and methods enabling the preparation of such nanotube/lipid complexes. Further disclosed is a method for therapeutics delivery that involves a drug delivery agent comprising a liposome with a NT loaded with a therapeutic agent, introducing the therapeutic agent into a cell or a tissue or an organism; and subsequent release of the therapeutic agents into a cell.
Information query
