Invention Application
- Patent Title: COMPOSITIONS AND METHODS COMPRISING BACTERIA FOR IMPROVING BEHAVIOR IN NEURODECELOPMENTAL DISORDERS
- Patent Title (中): 包含改善神经损伤行为的细菌的组合物和方法
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Application No.: PCT/US2015/057897Application Date: 2015-10-28
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Publication No.: WO2016069801A1Publication Date: 2016-05-06
- Inventor: HSIAO, Elaine , MCBRIDE, Sara , MAZMANIAN, Sarkis, K.
- Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
- Applicant Address: Office Of Technology Transfer 1200 E. California Blvd., Mail Code 6-32 Pasadena, CA 91125 US
- Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
- Current Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
- Current Assignee Address: Office Of Technology Transfer 1200 E. California Blvd., Mail Code 6-32 Pasadena, CA 91125 US
- Agency: ALTMAN, Daniel, E.
- Priority: US62/072,873 20141030
- Main IPC: A61P25/18
- IPC: A61P25/18 ; A61K35/74
Abstract:
Some embodiments include bacterial species for use in treatment of one or more autism spectrum disorder (ASD), and/or schizophrenia symptoms in a subject in need thereof. The bacterial species can include Bacteroides (e.g., B. fragilis, B. thetaiomlaomicron , and/or B. vulgatus ), and/or Enterococcus (e.g., E. faecalis, E.faecium, E. hirae, E. avium, E. durans, E. gallinarum , or E. casseliflavus ). Upon treatment, one or more ASD-related behaviors can be improved in the subject.
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