Invention Application
WO2016191247A1 RADIOACTIVE NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME
审中-公开
放射性纳米粒子及其制备方法和使用方法
- Patent Title: RADIOACTIVE NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME
- Patent Title (中): 放射性纳米粒子及其制备方法和使用方法
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Application No.: PCT/US2016/033432Application Date: 2016-05-20
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Publication No.: WO2016191247A1Publication Date: 2016-12-01
- Inventor: SUN, Xiankai , HAO, Yaowu , MOEENDARBARI, Sina
- Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: 201 West 7th Street Austin, TX 78701 US
- Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: 201 West 7th Street Austin, TX 78701 US
- Agency: WINBISH, J., Clinton et al.
- Priority: US14/719,921 20150522
- Main IPC: A61K51/12
- IPC: A61K51/12 ; A61K49/18 ; A61K103/00 ; A61K103/32 ; A61P35/00 ; B82Y15/00
Abstract:
In one aspect, radioactive nanoparticles are described herein. In some embodiments, a radioactive nanoparticle described herein comprises a metal nanoparticle core, an outer metal shell disposed over the metal nanoparticle core, and a metallic radioisotope disposed within the metal nanoparticle core or within the outer metal shell. In some cases, the radioactive nanoparticle has a size of about 30-500 ran in three dimensions. In addition, in some embodiments, the radioactive nanoparticle further comprises an inner metal shell disposed between the metal nanoparticle core and the outer metal shell. The metal nanoparticle core, outer metal shell, and inner metal shell of the radioactive nanoparticle can have various metallic compositions.
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