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    MACHINE LEARNING FOR THE DISCOVERY OF NANOMATERIAL-BASED MOLECULAR RECOGNITION
    2.
    发明申请
    MACHINE LEARNING FOR THE DISCOVERY OF NANOMATERIAL-BASED MOLECULAR RECOGNITION 审中-公开

    公开(公告)号：WO2023038939A1

    公开(公告)日：2023-03-16

    申请号：PCT/US2022/042710

    申请日：2022-09-07

    申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY

    发明人： GONG, Xun ,  RENEGAR, Nicholas ,  LEVI, Retsef ,  STRANO, Michael

    IPC分类号： G16C20/10 ,  B82Y15/00

    摘要： Computer program products, computer systems, and computer- implemented methods for making and using computational models for prediction of molecular recognition (MR) between a nanomaterial (NM) MR binder and an analyte. Methods for making a computational model involve selecting a candidate NM MR binder and conducting a physical test to determine whether MR occurs between the candidate NM MR binder and an analyte, and correlating features of the candidate NM MR binder with an experimental result obtained from the physical test to produce predictive information for the computational model. Methods for using the computational model involve receiving features of an untested candidate NM MR binder and analyzing the features to produce a prediction score that represents an expected experimental result of a physical test of the untested candidate MR binder and associating the prediction score with the untested candidate MR binder. The MR binder is a corona phase complex made from DNA adsorbed on a single wall carbon nanotube (SWCNT). The computational models include convolutional neural networks (CNN) and gradient boosted decision trees (GBDT).

    BIOFUNCTIONALIZED THREE-DIMENSIONAL (3D) GRAPHENE-BASED FIELD-EFFECT TRANSISTOR (FET) SENSOR
    3.
    发明申请
    BIOFUNCTIONALIZED THREE-DIMENSIONAL (3D) GRAPHENE-BASED FIELD-EFFECT TRANSISTOR (FET) SENSOR 审中-公开

    公开(公告)号：WO2023003893A1

    公开(公告)日：2023-01-26

    申请号：PCT/US2022/037614

    申请日：2022-07-19

    申请人： LYTEN, INC.

    发明人： LIM, Sung H. ,  DANIELSON, Eric Lewis ,  TARSIA, Maurizio ,  LARSEN, Gary Robert

    IPC分类号： G01N27/414 ,  B82Y15/00 ,  G01N33/00

    摘要： A biological field-effect transistor (BioFET) (100) includes source and drain regions (106, 108) formed in a substrate, an insulating layer (110) disposed on a surface of the substrate, a gate (120) disposed on the insulating layer and extending between the source and drain regions, a well region (140) containing an electrolyte solution (104) configured to retain an analyte (160), a three-dimensional (3D) graphene layer (130) forming a channel region in the substrate, and a passivation layer. The graphene layer is biofunctionalized with a molecular recognition element (144) configured to alter one or more electrical properties of the 3D graphene layer in response to exposure of the molecular recognition element to the analyte. The passivation layer is configured to prevent the electrolyte solution from contacting the source and drain. In some aspects, the 3D graphene layer is produced from carbon-containing inks. In other aspects, the 3D graphene layer includes a convoluted 3D structure configured to prevent graphene restacking.

    AN ELECTROMAGNETIC RADIATION DETECTOR, A MATRIX AND A METHOD FOR DETECTING RADIATION
    8.
    发明申请
    AN ELECTROMAGNETIC RADIATION DETECTOR, A MATRIX AND A METHOD FOR DETECTING RADIATION 审中-公开

    公开(公告)号：WO2022191736A1

    公开(公告)日：2022-09-15

    申请号：PCT/RU2021/050283

    申请日：2021-09-01

    申请人： BOCHAROV, Aleksey ,  KLESHCH, Viktor ,  KNYAZEV, Maksim ,  OBRAZTSOV, Petr ,  OBRAZTSOV, Aleksandr

    发明人： BOCHAROV, Aleksey ,  KLESHCH, Viktor ,  KNYAZEV, Maksim ,  OBRAZTSOV, Petr ,  OBRAZTSOV, Aleksandr

    IPC分类号： H01L31/036 ,  G01R19/00 ,  B82Y15/00

    摘要： The invention relates to a device for detecting electromagnetic radiation in the spectral range, including ultraviolet, visible, infrared and terahertz (millimeter and submillimeter), by converting the radiation energy into an electrical signal in the form of charge, current or voltage. An individual detector, as well as each sensitive element of the matrix, according to the invention, contains a photosensitive material in the form of a film of graphene-like material and a pair of electrodes, one of which covers the irradiated region of the photosensitive material, and the other is located in its center. The technical effect of increasing the sensitivity and decreasing the measurement time is achieved by matching the shape of the external electrode and the cross- section of the incident radiation beam. Also, by combining the elements of the matrix into columns and rows and alternately measuring the electrical signals arising under the action of radiation in the elements of the matrix, a decrease in the total number of electrodes required to ensure the operation of the matrix is achieved.

    HIGHLY STABLE METAL HALIDE PEROVSKITE COLLOIDAL COMPOSITIONS
    9.
    发明申请
    HIGHLY STABLE METAL HALIDE PEROVSKITE COLLOIDAL COMPOSITIONS 审中-公开

    公开(公告)号：WO2022177699A2

    公开(公告)日：2022-08-25

    申请号：PCT/US2022/013454

    申请日：2022-01-24

    申请人： UNIVERSITY OF KANSAS

    发明人： GONG, Maogang ,  WU, Judy Z.

    IPC分类号： B82Y15/00 ,  B82Y40/00 ,  C09K11/08 ,  B01J13/0026 ,  B01J13/0034 ,  B01J13/02

    摘要： Stabilized colloidal compositions and methods of making and using the compositions are provided. In embodiments, a stabilized colloidal composition comprises metal halide perovskite nanocrystals dispersed within a liquid phase medium comprising a synthesis solution from which the metal halide perovskite nanocrystals were synthesized, the synthesis solution comprising a dynamic binding compound capable of forming a covalent bond to surfaces of the metal halide perovskite nanocrystals as a dynamic binding ligand; and a stability promoter.