发明申请
- 专利标题： THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF
- 专利标题（中）： 治疗化合物及其使用方法
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申请号： PCT/US2016/054011申请日： 2016-09-27
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公开(公告)号： WO2017058821A1公开(公告)日： 2017-04-06
- 发明人: BERGERON, Phillipe , BURFORD, Kristen , CHOWDHURY, Sultan , DEHNHARDT, Christoph Martin , FOCKEN, Thilo , GRIMWOOD, Michael Edward , HASAN, Abid , LAI, Kwong Wah , LIU, Zhiguo , MCKERRALL, Steven , NGUYEN, Teresa Phuongtram , SAFINA, Brian , SUTHERLIN, Daniel , TAN, Wang Tao
- 申请人： GENENTECH, INC. , XENON PHARMACEUTICALS INC.
- 申请人地址： 1 DNA Way South San Francisco, California 94080-4990 US
- 专利权人： GENENTECH, INC.,XENON PHARMACEUTICALS INC.
- 当前专利权人： GENENTECH, INC.,XENON PHARMACEUTICALS INC.
- 当前专利权人地址： 1 DNA Way South San Francisco, California 94080-4990 US
- 代理机构： HARRIS, Robert J. et al.
- 优先权： US62/233,863 20150928; US62/298,817 20160223; CNPCT/CN2016/096659 20160825
- 主分类号： C07D417/12
- IPC分类号： C07D417/12 ; C07D417/14 ; A61K31/445 ; A61P29/00
摘要：
The invention provides a compound of formula: or a salt thereof, wherein the variables R AA , n, ring A, ring B, R 1a , R 1b , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , and R 9 have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.
