Invention Application
WO2017059003A1 BIOMARKERS AND METHODS FOR ASSESSING PSORIATIC ARTHRITIS DISEASE ACTIVITY
审中-公开
生物标记物和评估类风湿性关节炎疾病活动的方法
- Patent Title: BIOMARKERS AND METHODS FOR ASSESSING PSORIATIC ARTHRITIS DISEASE ACTIVITY
- Patent Title (中): 生物标记物和评估类风湿性关节炎疾病活动的方法
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Application No.: PCT/US2016/054323Application Date: 2016-09-29
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Publication No.: WO2017059003A1Publication Date: 2017-04-06
- Inventor: SASSO, Eric , EASTMAN, Paul Scott , BOLCE, Rebecca , KAVANAUGH, Arthur
- Applicant: SASSO, Eric , EASTMAN, Paul Scott , BOLCE, Rebecca , KAVANAUGH, Arthur , CRESCENDO BIOSCIENCE , UNIVERSITY OF CALIFORNIA SAN DIEGO
- Applicant Address: c/o Crescendo Bioscience 341 Oyster Point Blvd. South San Francisco, California 94080 US
- Assignee: SASSO, Eric,EASTMAN, Paul Scott,BOLCE, Rebecca,KAVANAUGH, Arthur,CRESCENDO BIOSCIENCE,UNIVERSITY OF CALIFORNIA SAN DIEGO
- Current Assignee: SASSO, Eric,EASTMAN, Paul Scott,BOLCE, Rebecca,KAVANAUGH, Arthur,CRESCENDO BIOSCIENCE,UNIVERSITY OF CALIFORNIA SAN DIEGO
- Current Assignee Address: c/o Crescendo Bioscience 341 Oyster Point Blvd. South San Francisco, California 94080 US
- Agency: ELLIS, Gregory
- Priority: US62/234,526 20150929
- Main IPC: G01N33/68
- IPC: G01N33/68 ; G01N33/536 ; G06F19/18
Abstract:
Provided herein are biomarkers and methods for generating scores useful for assessing psoriatic arthritis (PsA) disease activity in subjects previously diagnosed with PsA. The invention also provides predictive model methods based on the biomarkers, as well as computer systems, software embodiments of the models for scoring and optionally classifying samples, and methods of recommending optimal therapeutic regimens.
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