Invention Application
WO2017062901A3 METHODS TO ISOLATE EXTRACELLULAR VESICLES IN BIOFLUIDS FOR BIOMARKER DISCOVERY AND DISEASE DIAGNOSIS
审中-公开
在生物流体中分离细胞外生物标记物用于生物标记物发现和疾病诊断的方法
- Patent Title: METHODS TO ISOLATE EXTRACELLULAR VESICLES IN BIOFLUIDS FOR BIOMARKER DISCOVERY AND DISEASE DIAGNOSIS
- Patent Title (中): 在生物流体中分离细胞外生物标记物用于生物标记物发现和疾病诊断的方法
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Application No.: PCT/US2016056172Application Date: 2016-10-07
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Publication No.: WO2017062901A3Publication Date: 2017-05-26
- Inventor: TAO ANDY , ILYUK ANTON , BAO NING
- Applicant: TYMORA ANALYTICAL OPERATIONS LLC
- Assignee: TYMORA ANALYTICAL OPERATIONS LLC
- Current Assignee: TYMORA ANALYTICAL OPERATIONS LLC
- Priority: US201562238693 2015-10-07
- Main IPC: C12M1/42
- IPC: C12M1/42 ; C12N13/00 ; G01N27/00 ; G01N30/00 ; G01N33/50 ; H03K3/64
Abstract:
EVs are connected to onset and progression of numerous diseases and can be used for their diagnosis. Methods and platform technology to isolate EVs and detect intravesicle phosphoproteins from biofluids are discussed. Secreted extracellular vesicles in biofluids are effectively isolated and phosphoproteins are extracted for detection and identification as biomarkers for disease diagnosis using antibodies, mass spectrometry, or other like methods.
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