发明申请
WO2017161456A1 POLYNUCLEOTIDE COMPLEXES HAVING IMPROVED DELIVERY INTO CELLS
审中-公开
多核苷酸复合物具有改善的递送进入细胞
- 专利标题： POLYNUCLEOTIDE COMPLEXES HAVING IMPROVED DELIVERY INTO CELLS
- 专利标题（中）： 多核苷酸复合物具有改善的递送进入细胞
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申请号： PCT/CA2017/050367申请日： 2017-03-23
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公开(公告)号： WO2017161456A1公开(公告)日： 2017-09-28
- 发明人: EUDES, François , PEPPER, Jordan
- 申请人： HER MAJESTY THE QUEEN IN RIGHT OF CANADA, as represented by THE MINISTER OF AGRICULTURE AND AGRI-FOOD
- 申请人地址： Agriculture and Agri-Food Canada 5403-1 Avenue South Lethbridge, Alberta T1J 4B1 CA
- 专利权人： HER MAJESTY THE QUEEN IN RIGHT OF CANADA, as represented by THE MINISTER OF AGRICULTURE AND AGRI-FOOD
- 当前专利权人： HER MAJESTY THE QUEEN IN RIGHT OF CANADA, as represented by THE MINISTER OF AGRICULTURE AND AGRI-FOOD
- 当前专利权人地址： Agriculture and Agri-Food Canada 5403-1 Avenue South Lethbridge, Alberta T1J 4B1 CA
- 代理机构： MOFFAT & CO.
- 优先权： US62/312,707 20160324
- 主分类号： C12N15/87
- IPC分类号： C12N15/87 ; A61K31/713 ; A61K47/24 ; A61K47/42 ; A61K48/00 ; C12N15/10 ; C12N15/113 ; C07H21/02
摘要：
Compositions including a nanocomplex of a polynucleotide with a cell-penetrating peptide and a quaternary phosphonium salt, such as tetrabutylphosphonium bromide (TBPB), are useful for delivering polynucleotides such as DNA or RNA into cells.
IPC分类:
