发明申请
WO2018029182A1 IL-6R SINGLE VARIABLE DOMAIN ANTIBODIES FOR TREATMENT OF IL-6R RELATED DISEASES
审中-公开
IL-6R单变量抗体治疗IL-6R相关疾病
- 专利标题： IL-6R SINGLE VARIABLE DOMAIN ANTIBODIES FOR TREATMENT OF IL-6R RELATED DISEASES
- 专利标题（中）： IL-6R单变量抗体治疗IL-6R相关疾病
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申请号： PCT/EP2017/070045申请日： 2017-08-08
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公开(公告)号： WO2018029182A1公开(公告)日： 2018-02-15
- 发明人: HOEFMAN, Sven , SARGENTINI-MAIER, Maria-Laura , VAN BENEDEN, Katrien
- 申请人： ABLYNX N.V.
- 申请人地址： Technologiepark 21 9052 Ghent-Zwijnaarde BE
- 专利权人： ABLYNX N.V.
- 当前专利权人： ABLYNX N.V.
- 当前专利权人地址： Technologiepark 21 9052 Ghent-Zwijnaarde BE
- 代理机构： HOFFMANN EITLE PATENT- UND RECHTSANWÄLTE PARTMBB et al.
- 优先权： US62/372,017 20160808; US62/518,738 20170613
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; C07K16/28 ; A61K39/395 ; A61K31/519
摘要：
Methods are provided for the treatment of IL-6R related diseases involving a combination therapy. More specifically, specific dose regimens and pre-filled syringes are provided for subcutaneous administration, to subjects suffering an IL-6R related disease, of immunoglobulin single variable domains that bind IL-6R, in combination with at least one additional therapeutic agent, such as methotrexate.
