发明申请
WO2018075842A1 CONDENSED BENZODIAZEPINE DERIVATIVES AND CONJUGATES MADE THEREFROM
审中-公开
缩合苯并二氮杂衍生物及由其制成的缀合物
- 专利标题： CONDENSED BENZODIAZEPINE DERIVATIVES AND CONJUGATES MADE THEREFROM
- 专利标题（中）： 缩合苯并二氮杂衍生物及由其制成的缀合物
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申请号： PCT/US2017/057508申请日： 2017-10-20
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公开(公告)号： WO2018075842A1公开(公告)日： 2018-04-26
- 发明人: MCDONALD, Ivar M. , SIVAPRAKASAM, Prasanna , IWUAGWU, Christiana I. , PEESE, Kevin M. , CHENG, Heng , CHOWDARI, Naidu S. , GANGWAR, Sanjeev
- 申请人： BRISTOL-MYERS SQUIBB COMPANY
- 申请人地址： Route 206 and Province Line Road Princeton, New Jersey 08543 US
- 专利权人： BRISTOL-MYERS SQUIBB COMPANY
- 当前专利权人： BRISTOL-MYERS SQUIBB COMPANY
- 当前专利权人地址： Route 206 and Province Line Road Princeton, New Jersey 08543 US
- 代理机构： GOLIAN, Paul D. et al.
- 优先权： US62/410,624 20161020
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/5513 ; A61P35/00
摘要：
A compound capable of inhibiting cell proliferation, having a structure according to formula (I) wherein the variables in formula (I) are as defined in the specification. Such compounds are useful as anti-cancer agents, especially in antibody-drug conjugates.
