- 专利标题： 18F-LABELED COMPOUNDS FOR PET IMAGING AND USES THEREOF
-
申请号： PCT/US2017/057595申请日： 2017-10-20
-
公开(公告)号： WO2018128664A2公开(公告)日： 2018-07-12
- 发明人: LI, Zibo , WU, Zhanhong , GIGLIO, Ben , MOSCHOS, Stergios
- 申请人： THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
- 申请人地址： 109 Church St. Chapel Hill, North Carolina 27516 US
- 专利权人： THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
- 当前专利权人： THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
- 当前专利权人地址： 109 Church St. Chapel Hill, North Carolina 27516 US
- 代理机构： SCHWARTZMAN, Robert A.
- 优先权： US62/410,681 20161020
摘要：
The present invention relates to 18 F-labeled compounds suitable for positron emission tomography (PET) imaging. The invention further relates to the use of these compounds for carrying out PET scans, imaging the indoleamine 2,3-dioxygenase, pathway, predicting the responsiveness of a subject with a solid tumor to therapies including immunotherapy such as PD-1/PD-L1 inhibition, and determining whether a solid tumor in a subject contains tumor-infiltrating immune cells.
公开/授权文献
- WO2018128664A3 18F-LABELED COMPOUNDS FOR PET IMAGING AND USES THEREOF 公开/授权日：2018-07-12
