专利检索 ap:("THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL") AND inv:"GIGLIO, Ben" 第 1 页

1.

发明申请
18F-LABELED COMPOUNDS FOR PET IMAGING AND USES THEREOF 审中-公开

公开(公告)号：WO2018128664A3

公开(公告)日：2018-07-12

申请号：PCT/US2017/057595

申请日：2017-10-20

申请人： THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

发明人： LI, Zibo , WU, Zhanhong , GIGLIO, Ben , MOSCHOS, Stergios

IPC分类号： A61K49/06 , A61K51/00 , A61K31/404 , A61P35/00 , A61K101/02

摘要： The present invention relates to 18 F-labeled compounds suitable for positron emission tomography (PET) imaging. The invention further relates to the use of these compounds for carrying out PET scans, imaging the indoleamine 2,3-dioxygenase, pathway, predicting the responsiveness of a subject with a solid tumor to therapies including immunotherapy such as PD-1/PD-L1 inhibition, and determining whether a solid tumor in a subject contains tumor-infiltrating immune cells.

2.

发明申请
18F-LABELED COMPOUNDS FOR PET IMAGING AND USES THEREOF 审中-公开

公开(公告)号：WO2018128664A2

公开(公告)日：2018-07-12

申请号：PCT/US2017/057595

申请日：2017-10-20

申请人： THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

发明人： LI, Zibo , WU, Zhanhong , GIGLIO, Ben , MOSCHOS, Stergios

CPC分类号： A61K51/0406 , A61K2123/00 , A61P35/00 , C07B59/002 , C07B2200/05

摘要： The present invention relates to 18 F-labeled compounds suitable for positron emission tomography (PET) imaging. The invention further relates to the use of these compounds for carrying out PET scans, imaging the indoleamine 2,3-dioxygenase, pathway, predicting the responsiveness of a subject with a solid tumor to therapies including immunotherapy such as PD-1/PD-L1 inhibition, and determining whether a solid tumor in a subject contains tumor-infiltrating immune cells.