Invention Application
- Patent Title: INHIBITION OF OXIDATIVE STRESS, GLYCATION, AND PROTEIN CROSSLINKING
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Application No.: PCT/US2018/046442Application Date: 2018-08-13
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Publication No.: WO2019036336A1Publication Date: 2019-02-21
- Inventor: NAGARAJ, Ram , LINETSKY, Mikhail , RAKETE, Stefan , NAHOMI, Rooban
- Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
- Applicant Address: 1800 Grant Street 8th Floor Denver, Colorado 80203 US
- Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
- Current Assignee Address: 1800 Grant Street 8th Floor Denver, Colorado 80203 US
- Agency: TRAVER, Robert D.
- Priority: US62/545,149 20170814
- Main IPC: A61K31/7088
- IPC: A61K31/7088 ; A61K38/54 ; A61K45/06
Abstract:
Compositions for the treatment and prevention of symptoms and disease conditions associated with oxidative and carbonyl stress, including advanced glycation end products (AGEs), and to methods using the compositions. In particular, the invention relates to compositions useful in the treatment of diabetic retinopathy and nephropathy, to compositions useful in the treatment of other retinal disorders including macular degeneration and cataracts.
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