- 专利标题： NOVEL SUBSTITUTED CYCLOBUTYLPYRIDINE AND CYCLOBUTYLPYRIMIDINE COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS
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申请号： PCT/US2018/054276申请日： 2018-10-04
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公开(公告)号： WO2019074749A1公开(公告)日： 2019-04-18
- 发明人: WHITE, Catherine M. , ACHAB, Abdelghani , BHARATHAN, Indu T. , FRADERA, Xavier , HAN, Yongxin , LI, Derun , LIM, Jongwon , LIU, Kun , MCGOWAN, Meredeth Ann , SCIAMMETTA, Nunzio , YU, Wensheng , ZHANG, Hongjun , ZHOU, Hua
- 申请人： MERCK SHARP & DOHME CORP. , WHITE, Catherine M. , ACHAB, Abdelghani , BHARATHAN, Indu T. , FRADERA, Xavier , HAN, Yongxin , LI, Derun , LIM, Jongwon , LIU, Kun , MCGOWAN, Meredeth Ann , SCIAMMETTA, Nunzio , YU, Wensheng , ZHANG, Hongjun , ZHOU, Hua
- 申请人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 专利权人： MERCK SHARP & DOHME CORP.,WHITE, Catherine M.,ACHAB, Abdelghani,BHARATHAN, Indu T.,FRADERA, Xavier,HAN, Yongxin,LI, Derun,LIM, Jongwon,LIU, Kun,MCGOWAN, Meredeth Ann,SCIAMMETTA, Nunzio,YU, Wensheng,ZHANG, Hongjun,ZHOU, Hua
- 当前专利权人： MERCK SHARP & DOHME CORP.,WHITE, Catherine M.,ACHAB, Abdelghani,BHARATHAN, Indu T.,FRADERA, Xavier,HAN, Yongxin,LI, Derun,LIM, Jongwon,LIU, Kun,MCGOWAN, Meredeth Ann,SCIAMMETTA, Nunzio,YU, Wensheng,ZHANG, Hongjun,ZHOU, Hua
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 代理机构： MERCK SHARP & DOHME CORP.
- 优先权： US62/569,886 20171009
- 主分类号： A61K31/166
- IPC分类号： A61K31/166 ; C07C13/06 ; C07C233/65
摘要：
Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.
