Provided herein are compounds and methods of using compounds for preventing or treating peripheral nerve damage in a subject in need of such prevention or treatment. In particular, provided herein are compounds and methods of using compounds for the prevention of peripheral nerve damage from chemotherapy, metabolic dysfunction, surgery/trauma, and other causes (PND). More particularly, provided herein are compounds and methods of using compounds as neuroprotective agents which are compounds that inhibit sodium channels that allow peripheral nociceptive neurons to signal to the central nervous system, such as the compounds of Formula (I) or compounds of Formula (I').