Methods, systems, and computer readable media for analyzing an image using machine learning and human computation. A method for analyzing an image includes providing, via multiple instances of an interactive application (334) for analysis of the image, multiple instances, respectively, of the image and receiving, via the interactive application, data (240) from results of analyses of the image including multiple sets of user inputs from the analyses of the multiple instances of the image, respectively. The multiple sets of user inputs are from multiple users, respectively and the multiple users are associated with the multiple instances of the interactive application, respectively. The method further includes processing the received data to identify areas of interest within the image based on the multiple sets of user inputs and analyzing the image using a machine learning algorithm (245) to identify structures in the image based on the identified areas of interest within the image.