- 专利标题: SUBSTITUTED BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF
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申请号: PCT/US2019/050900申请日: 2019-09-12
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公开(公告)号: WO2020056198A3公开(公告)日: 2020-03-19
- 发明人: COBURN, Craig Alan , SMITH, Sean Wesley
- 申请人: SILVERBACK THERAPEUTICS, INC.
- 申请人地址: 500 Fairview Avenue North Suite 600 Seattle, Washington 98109 US
- 专利权人: SILVERBACK THERAPEUTICS, INC.
- 当前专利权人: SILVERBACK THERAPEUTICS, INC.
- 当前专利权人地址: 500 Fairview Avenue North Suite 600 Seattle, Washington 98109 US
- 代理机构: SUSANTO, Christina
- 优先权: US62/730,492 20180912
- 主分类号: C07D403/10
- IPC分类号: C07D403/10 ; A61K31/55 ; A61P35/00 ; A61P37/00
摘要:
Benzazepine compounds and salts thereof, conjugates and pharmaceutical compositions for use in the treatment of disease, such as cancer, are disclosed herein. The disclosed benzazepine compounds and salts thereof are useful, among other things, in treating of cancer and activating an immune response. Additionally, benzazepine compounds or salts thereof attached to an antibody construct to form an antibody conjugate are described herein.
公开/授权文献