- 专利标题： COMPOUNDS AND THEIR USE FOR THE TREATMENT OF α1-ANTITRYPSIN DEFICIENCY
-
申请号： PCT/GB2019/053552申请日： 2019-12-13
-
公开(公告)号： WO2020120992A1公开(公告)日： 2020-06-18
- 发明人: RAMSDEN, Nigel , FOX, David , HUNTINGTON, James Andrew
- 申请人： Z FACTOR LIMITED
- 申请人地址： Moneta Building Babraham Research Campus Babraham Cambridge GB
- 专利权人： Z FACTOR LIMITED
- 当前专利权人： Z FACTOR LIMITED
- 当前专利权人地址： Moneta Building Babraham Research Campus Babraham Cambridge GB
- 代理机构： REDDIE & GROSE LLP
- 优先权： GB1820450.3 20181214
- 主分类号： C07D239/36
- IPC分类号： C07D239/36 ; A61K31/513 ; A61P1/16 ; A61P11/06 ; A61P11/08
摘要：
The invention relates to oxopyrimidinyl-methyl-benzamide derivatives, for example in a pharmaceutically acceptable salt form or crystal form, pharmaceutical compositions comprising the derivatives, and their medical use, in particular for use in the treatment of α1-antitrypsin deficiency (A1AD or AATD).
