- 专利标题： COMMON LIGHT CHAINS AND METHODS OF USE
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申请号： PCT/US2020/025189申请日： 2020-03-27
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公开(公告)号： WO2020205504A1公开(公告)日： 2020-10-08
- 发明人: LAJOIE, Jason Michael , SCHMIDT, Michael March
- 申请人： COMPASS THERAPEUTICS LLC
- 申请人地址： 245 First Street, 3rd floor Cambridge, Massachusetts 02142 US
- 专利权人： COMPASS THERAPEUTICS LLC
- 当前专利权人： COMPASS THERAPEUTICS LLC
- 当前专利权人地址： 245 First Street, 3rd floor Cambridge, Massachusetts 02142 US
- 代理机构： BRYAN, Jennifer F. et al.
- 优先权： US62/826,535 20190329
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00 ; C07K16/46 ; C07K19/00 ; C12N15/09 ; C12N15/13
摘要：
The present disclosure provides methods of generating multispecific antigen-binding molecules comprising a common light chain compatible with two or more different heavy chains. The present disclosure further provides methods of identifying common light chains that are compatible with two or more different heavy chains
