- 专利标题： OPTIMIZED ANTI-FLT1 OLIGONUCLEOTIDE COMPOUNDS FOR TREATMENT OF PREECLAMPSIA AND OTHER ANGIOGENIC DISORDERS
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申请号： PCT/US2022/034461申请日： 2022-06-22
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公开(公告)号： WO2022271786A1公开(公告)日： 2022-12-29
- 发明人: HARIHARAN, Vignesh Narayan , KARUMANCHI, Ananth , KHVOROVA, Anastasia , DAVIS, Sarah , BISCANS, Annabelle
- 申请人： UNIVERSITY OF MASSACHUSETTS , BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
- 申请人地址： One Beacon Street, 31st Floor; 330 Brookline Avenue
- 专利权人： UNIVERSITY OF MASSACHUSETTS,BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
- 当前专利权人： UNIVERSITY OF MASSACHUSETTS,BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
- 当前专利权人地址： One Beacon Street, 31st Floor; 330 Brookline Avenue
- 代理机构： SPELLBERG, Michael et al.
- 优先权： US63/214,224 2021-06-23
- 主分类号： C12N15/113
- IPC分类号： C12N15/113
摘要：
This disclosure relates to novel targets for angiogenic disorders. Novel oligonucleotides are also provided. Methods of using the novel oligonucleotides for the treatment of angiogenic disorders (e.g., preeclampsia) are also provided.
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