Invention Application
- Patent Title: SYNTHETIC RNAS AND USES THEREOF
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Application No.: PCT/US2022/074648Application Date: 2022-08-08
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Publication No.: WO2023015319A1Publication Date: 2023-02-09
- Inventor: BROWN, Judith K. , MONDAL, Mosharrof Hossain , PAREDES MONTERO, Jorge Rafael , FLYNT, Alex
- Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA , THE UNIVERSITY OF SOUTHERN MISSISSIPPI
- Applicant Address: The University of Arizona, Tech Launch Arizona; 118 College Drive, #5012
- Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA,THE UNIVERSITY OF SOUTHERN MISSISSIPPI
- Current Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA,THE UNIVERSITY OF SOUTHERN MISSISSIPPI
- Current Assignee Address: The University of Arizona, Tech Launch Arizona; 118 College Drive, #5012
- Agency: HULLINGER, Rikki A.
- Priority: US63/230,560 2021-08-06
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/01
Abstract:
Provided herein are synthetic RNAs comprising a piRNA sequence and a target sequence for a gene of interest. The synthetic RNAs find use in methods of gene editing, in particular in methods of silencing expression of the gene of interest.
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