- 专利标题： USES OF GAMMA DELTA T CELL ACTIVATING ANTIBODIES
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申请号： PCT/EP2022/079374申请日： 2022-10-21
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公开(公告)号： WO2023067138A1公开(公告)日： 2023-04-27
- 发明人: VAN DER VLIET, Johannes Jelle , PARREN, Paul Willem Henri Ida , RUBEN, Jurjen Matthijs , ENSING, Erik
- 申请人： LAVA THERAPEUTICS N.V.
- 申请人地址： Yalelaan 60
- 专利权人： LAVA THERAPEUTICS N.V.
- 当前专利权人： LAVA THERAPEUTICS N.V.
- 当前专利权人地址： Yalelaan 60
- 代理机构： NEDERLANDSCH OCTROOIBUREAU
- 优先权： EP21204014.1 2021-10-21
- 主分类号： A61K31/663
- IPC分类号： A61K31/663 ; A61K35/17 ; A61K39/395 ; A61P35/00 ; C07K16/28 ; A61K31/675 ; A61K45/06 ; A61K2039/505 ; A61K2039/545 ; A61K2039/57 ; A61K39/39558 ; C07K16/2809 ; C07K16/2833 ; C07K2317/22 ; C07K2317/31 ; C07K2317/569 ; C07K2317/73 ; C07K2317/75
摘要：
The present invention relates to novel uses of gamma delta T-cell activating antibodies, in particular uses of such antibodies in patients that are also being treated, or have recently been treated, with aminobisphosphonates, or other inhibitors of the mevalonate pathway that inhibit farnesyl pyrophosphate synthase or an enzyme further downstream in the mevalonate pathway.
