- 专利标题: COMPOSITIONS AND METHODS OF TREATMENT FOR CANCERS
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申请号: PCT/US2022/079187申请日: 2022-11-02
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公开(公告)号: WO2023081733A1公开(公告)日: 2023-05-11
- 发明人: DESELM, Carl , NAMEN, Shelby
- 申请人: WASHINGTON UNIVERSITY
- 申请人地址: One Brookings Drive
- 专利权人: WASHINGTON UNIVERSITY
- 当前专利权人: WASHINGTON UNIVERSITY
- 当前专利权人地址: One Brookings Drive
- 代理机构: GALANT, Ron et al.
- 优先权: US63/274,854 2021-11-02
- 主分类号: C07K14/705
- IPC分类号: C07K14/705 ; A61K35/17 ; A61P35/00 ; C07K16/28 ; C12N5/0783
摘要:
Among the various aspects of the present disclosure is the provision of compositions and methods of making modified chimeric antigen receptor dendritic cells (CAR-DCs) and methods of use thereof. CAR-DCs can be used for the treatment of tumors and cancers, particularly solid tumors (as well as liquid tumors, blood cancer, and metastatic cancer).