公开(公告)号：EP1358357A1

公开(公告)日：2003-11-05

申请号：EP02716498.7

申请日：2002-01-11

申请人： Biomolex AS

发明人： HOVIG, Eivind ,  SKRETTING, Arne ,  NYGARD, Einar ,  KVINNSLAND, Yngve ,  BREISTOL, Knut ,  YOSHIOKA, Koki

IPC分类号： C12Q1/68 ,  G01N33/543 ,  G01T1/164

CPC分类号： C40B30/04 ,  C12Q1/6816 ,  C12Q1/6837 ,  G01N33/60 ,  G01N33/6842 ,  G01N33/6845 ,  C12Q2565/501 ,  C12Q2563/101 ,  C12Q2545/114

摘要： The present invention relates to a method and apparatus for simultaneous quantification of the amounts of one or more radioactive nuclides within arbitrary regions on a surface where these nuclides have been deposited, adsorbed or fixed. These radioactive nuclides serve as markers on compounds that typically have been incorporated into tissue sections or into larger biological molecules that by various mechanisms have been bound to chemical substances on this surface. The method is especially well suited for DNA microarray deductions through the use of nucleotides labelled with different beta-emitting radionuclides.

公开(公告)号：EP1358357B1

公开(公告)日：2011-03-09

申请号：EP02716498.7

申请日：2002-01-11

申请人： Biomolex AS

发明人： HOVIG, Eivind ,  SKRETTING, Arne ,  NYGARD, Einar ,  KVINNSLAND, Yngve ,  BREISTOL, Knut ,  YOSHIOKA, Koki

IPC分类号： C12Q1/68 ,  G01N33/543 ,  G01T1/164

CPC分类号： C40B30/04 ,  C12Q1/6816 ,  C12Q1/6837 ,  G01N33/60 ,  G01N33/6842 ,  G01N33/6845 ,  C12Q2565/501 ,  C12Q2563/101 ,  C12Q2545/114

摘要： The present invention relates to a method and apparatus for simultaneous quantification of the amounts of one or more radioactive nuclides within arbitrary regions on a surface where these nuclides have been deposited, adsorbed or fixed. These radioactive nuclides serve as markers on compounds that typically have been incorporated into tissue sections or into larger biological molecules that by various mechanisms have been bound to chemical substances on this surface. The method is especially well suited for DNA microarray deductions through the use of nucleotides labelled with different beta-emitting radionuclides.