公开(公告)号：EP4119193A1

公开(公告)日：2023-01-18

申请号：EP20919583.3

申请日：2020-10-29

申请人： JBM Incorporation ,  GN Corporation Co Ltd

发明人： KATOH, Shojiro ,  ABRAHAM, Samuel JK

IPC分类号： A61P13/00 ,  A61P43/00 ,  C12N5/071 ,  C12N5/074 ,  A61K35/36 ,  A61K35/37 ,  A61L27/36 ,  A61L27/38

摘要： The purpose of the present invention is to provide: a method for maintaining or enhancing the activity of a cell mass separated from an epithelial tissue; a method for increasing the proliferation ability of cells in an epithelial tissue; a method for producing a cell mass employing these methods; a pharmaceutical composition containing the cell mass; and a method for treating a disease using the cell mass. The purpose can be solved by culturing a cell mass separated from an epithelial tissue or an epithelial tissue with a thermoreversible polymer.

公开(公告)号：EP3693033A1

公开(公告)日：2020-08-12

申请号：EP18864482.7

申请日：2018-10-01

申请人： GN Corporation Ltd ,  JBM Incorporation

发明人： YOSHIOKA Hiroshi ,  Samuel Abraham JK

IPC分类号： A61L31/04 ,  A61K9/08 ,  A61K35/22 ,  A61K35/38 ,  A61K47/30 ,  A61L31/14 ,  A61L31/16 ,  A61P13/02

摘要： [Object]
The present invention is intended to provide a urethral stricture treatment agent and a urethral stricture treatment method capable of avoiding restenosis by a less invasive transurethral endoscopic procedure in urethral stricture treatment.
[Solution]
A urethral stricture treatment agent including at least a hydrogel-forming polymer, and having a storage elastic modulus of 50 Pa or less at 10°C and a storage elastic modulus of 100 Pa or more at 37°C.
A urethral stricture treatment method at least including injecting the urethral stricture treatment agent cooled to 10°C or lower into an inner surface of urethra which has been incised with a transurethral endoscopic procedure, and holding the urethral stricture treatment agent in the inner surface of urethra at a temperature not lower than a room temperature.
[Selected Drawing]
None

公开(公告)号：EP3954761A1

公开(公告)日：2022-02-16

申请号：EP20787633.5

申请日：2020-04-08

申请人： GN Corporation Co Ltd ,  JBM Incorporation

发明人： KATO, Shojiro ,  ABRAHAM, Samuel JK ,  KUBOTA, Sunao

IPC分类号： C12N5/077

摘要： The purpose of the present invention is to provide a chondrocyte culture with high tissue regeneration ability. This purpose is met by a method involving a step in which a cell population separated from cartilage tissue is cultured on a thermoreversible polymer.