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    Method for identifying and characterizing organisms
    4.
    发明公开
    Method for identifying and characterizing organisms 失效
    识别和表征生物体的方法

    公开(公告)号：EP0120658A3

    公开(公告)日：1988-01-13

    申请号：EP84301800

    申请日：1984-03-16

    申请人： Webster, John A., Jr.

    发明人： Webster, John A., Jr.

    IPC分类号： C12Q01/68

    CPC分类号： C12Q1/6888 ,  C12Q1/683

    摘要： A method of characterizing an unknown organism species comprises determining the position of part or whole of evolutionarily conserved sequences in genetic material of said organism, relative to a known position of restriction endonuclease cleavage sites in said genetic material (other than by determining the chromatographic pattern of retriction endonuclease digested DNA from said unknown organism, which digested DNA has been hybridized or reassociated with ribosomal RNA information containing nucleic acid from or derived from a known probe organism), thereby to obtain an identifying genetic characterization of said unknown organism, and comparing said characterization with information from at least two sets of identifying genetic characterizations derived from the same conserved sequences, each of said sets defining a known organism species.

    摘要翻译： 表征未知生物种类的方法包括确定所述生物的遗传物质中进化保守序列的部分或全部相对于所述遗传物质中限制性内切核酸酶切割位点的已知位置的位置（除了通过确定所述生物体的色谱图谱 来自所述未知生物体的限制性内切核酸酶消化的DNA，其消化DNA已经与含有来自已知探针生物体或来源于已知探针生物体的核酸的核糖体RNA信息杂交或重新关联），从而获得所述未知生物体的鉴定遗传表征， 利用来自至少两组来自相同保守序列的鉴定遗传表征的信息，每个所述组定义已知有机体物种。

    Method for identifying and characterizing organisms
    5.
    发明公开
    Method for identifying and characterizing organisms 失效
    识别和表征生物体的方法

    公开(公告)号：EP0155360A1

    公开(公告)日：1985-09-25

    申请号：EP84113957.9

    申请日：1982-09-24

    申请人： Webster, John A., Jr.

    发明人： Webster, John A., Jr.

    IPC分类号： C12P19/34

    CPC分类号： C12Q1/689 ,  C12Q1/683 ,  C12Q1/6888

    摘要： A method of detecting a prokaryotic organism comprises selectively hybridising the DNA of the prokaryotic organism with a detectably labeled prokaryotic ribosomal RNA-information-containing hybridisation probe.

    摘要翻译： 检测原核生物的方法包括选择性地将原核生物的DNA与可检测标记的含原核核糖体RNA信息的杂交探针杂交。

    Method for identifying and characterizing organisms
    6.
    发明公开
    Method for identifying and characterizing organisms 失效
    Verfahren zur Identifizierung und Charakterisierung von Organismen。

    公开(公告)号：EP0155359A1

    公开(公告)日：1985-09-25

    申请号：EP84113956.1

    申请日：1982-09-24

    申请人： Webster, John A., Jr.

    发明人： Webster, John A., Jr.

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/6888 ,  C12Q1/683

    摘要： A method of characterizing and/or identifying an unknown organism which comprises comparing the chromatographic pattern of restriction endonuclease-digested DNA from the organism, which digested DNA has been reassociated or hybridized with ribosomal RNA-information containing nucleic acid from a probe organism, with equivalent chromatographic patterns of at least two known different organism species.

    摘要翻译： 表征和/或鉴定未知生物体的方法，其包括比较来自生物体的限制性内切核酸酶消化的DNA的色谱图，其中已消化的DNA已被重新结合或与来自探针生物体的含有核酸的核糖体RNA信息杂交，具有等同物 至少两种已知不同生物种的色谱图。

    Method for identifying and characterizing organisms
    7.
    发明公开
    Method for identifying and characterizing organisms 失效
    Verfahren zur Identifizierung und Charakterisierung von Organismen。

    公开(公告)号：EP0120658A2

    公开(公告)日：1984-10-03

    申请号：EP84301800.3

    申请日：1984-03-16

    申请人： Webster, John A., Jr.

    发明人： Webster, John A., Jr.

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/6888 ,  C12Q1/683

    摘要： A method of characterizing an unknown organism species comprises determining the position of part or whole of evolutionarily conserved sequences in genetic material of said organism, relative to a known position of restriction endonuclease cleavage sites in said genetic material (other than by determining the chromatographic pattern of retriction endonuclease digested DNA from said unknown organism, which digested DNA has been hybridized or reassociated with ribosomal RNA information containing nucleic acid from or derived from a known probe organism), thereby to obtain an identifying genetic characterization of said unknown organism, and comparing said characterization with information from at least two sets of identifying genetic characterizations derived from the same conserved sequences, each of said sets defining a known organism species.

    摘要翻译： 表征未知生物物种的方法包括相对于所述遗传物质中的限制性内切核酸酶切割位点的已知位置确定所述生物体的遗传物质中进化保守序列的部分或全部的位置（除了通过确定所述生物体的色谱图 来自所述未知生物体的重复性内切核酸酶消化的DNA，其已消化的DNA已经与含有来自或衍生自已知探针生物的核酸的核糖体RNA信息杂交或重新结合），从而获得所述未知生物体的鉴定遗传表征，并比较所述表征 具有来自相同保守序列的至少两组识别遗传表征的信息，所述组中的每一个限定了已知的生物体种类。

    Method for identifying and characterizing organisms
    8.
    发明公开
    Method for identifying and characterizing organisms 失效
    Verfahren zur Identifizierung und Charakterisierung von Organismen。

    公开(公告)号：EP0076123A1

    公开(公告)日：1983-04-06

    申请号：EP82305061.2

    申请日：1982-09-24

    申请人： Webster, John A., Jr.

    发明人： Webster, John A., Jr.

    IPC分类号： C12Q1/04 ,  C12Q1/68 ,  G01N33/48

    CPC分类号： C12Q1/689 ,  C12Q1/04 ,  C12Q1/683 ,  C12Q1/6888 ,  Y10S435/803

    摘要： A method of characterizing and/or identifying an unknown organism which comprises comparing the chromatographic pattern of restriction endonuclease-digested DNA from the organism, which digested DNA has been reassociated or hybridized with ribosomal RNA-information containing nucleic acid from a probe organism, with equivalent chromatographic patterns of at least two known different known organism species.

    摘要翻译： 表征未知生物体的方法，其包括比较来自未知生物体的限制性内切核酸酶 - 消化器DNA的色谱图，其中已消化的DNA已经与来自已知探针组织的来自核糖体RNA信息的核酸或从已知探针组织衍生的核糖体RNA信息杂交或重新结合， 至少两个等效的色谱图，每个等价色谱图定义了已知的不同生物种; 并通过存在于未知生物体的色谱图中的保守的核糖体RNA序列限制性片段来建立未知生物体的种类。