专利检索 ap:("ABBOTT LABORATORIES") AND inv:"FREY, Lisa, M." 第 1 页

1.

发明公开
TETRAHYDROISOQUINOLINE DERIVATIVES AS LHRH ANTAGONISTS 审中-公开
标题翻译： TETRAHYDROISOCHINOLINE衍生物在ALS LHRH受体拮抗剂

公开(公告)号：EP1129076A1

公开(公告)日：2001-09-05

申请号：EP99961631.1

申请日：1999-11-09

申请人： ABBOTT LABORATORIES

发明人： HAVIV, Fortuna , DWIGHT, Wesley, J. , CRAWFORD, Bradley, W. , SWENSON, Rolf, E. , BRUNCKO, Milan , KAMINSKI, Michele, A. , FREY, Lisa, M. , DEMATTEI, John , GREER, Jonathan

IPC分类号： C07D217/04 , C07D217/14 , C07D217/16 , A61K31/472 , A61P5/00 , C07D217/20 , C07D217/26 , C07D223/16 , C07D401/06 , C07D401/12 , C07D401/10 , C07D491/04 , C07D401/08

CPC分类号： C07D401/04 , C07D217/04 , C07D217/14 , C07D217/16 , C07D217/18 , C07D217/20 , C07D217/22 , C07D223/16 , C07D401/06 , C07D401/12 , C07D491/04

摘要： Tetrahydroisoquinoline derivatives of formula (I): or a pharmaceutically acceptable salt, ester, or prodrug thereof, having activity as an LHRH antagonist, as well as pharmaceutical compositions containing the same, and methods for their use and preparation.