专利检索 ap:("Abbott GmbH & Co. KG") AND inv:"CUSACK, Kevin, P." 第 1 页

1.

发明公开
2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS 审中-公开
标题翻译： 2 BENZOTHIAZOLYLHARNSTOFF衍生物及其作为激酶抑制剂的蛋白质

公开(公告)号：EP1254123A1

公开(公告)日：2002-11-06

申请号：EP01908878.0

申请日：2001-02-06

申请人： Abbott GmbH & Co. KG

发明人： CUSACK, Kevin, P. , SCOTT, Barbara , ARNOLD, Lee, D. , ERICSSON, Anna

IPC分类号： C07D277/82 , C07D417/04 , C07D417/12 , C07D417/06 , C07D453/02 , C07D451/02 , C07D451/14 , C07D513/04 , C07D487/08 , A61K31/428 , A61K31/435 , A61K31/53 , A61P35/00

CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D277/82 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14 , C07D451/02 , C07D451/04 , C07D451/14 , C07D453/02 , C07D487/08 , C07D513/04

摘要： The present invention is directed to a compound of formula (I), racemic-diastereomeric mixtures thereof, optical isomers thereof, prodrugs thereof, isotopes thereof or pharmaceutically-acceptable salts of said compound, isomers, prodrugs and isotopes, wherein the variable are defined herein. The compounds of this invention are useful as inhibitors of serine/threonine and tyrosine kinases. In particular, compounds of this invention are useful as inhibitors of tyrosine kinases that are important in hyperproliferative diseases, especially in cancer and in the process of angiogenesis.