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公开(公告)号：EP1893578A2
公开(公告)日：2008-03-05
申请号：EP06765703.1
申请日：2006-05-23
发明人： BEZENCON, Olivier , BOSS, Christoph , BUR, Daniel , CHEN, Austin, Chih-Yu , CORMINBOEUF, Olivier , DUBE, Daniel , FISCHLI, Walter , GRISOSTOMI, Corinna , REMEN, Lubos , RICHARD-BILDSTEIN, Sylvia , SIFFERLEN, Thierry , THERIEN, Michel , WELLER, Thomas
IPC分类号： C07D211/78 , C07D471/08 , C07D401/10 , A61K31/451 , C07D401/12 , A61P9/00
CPC分类号： C07D471/08 , C07D211/78 , C07D401/10 , C07D401/12
摘要： The invention relates to novel piperidine carboxylic acid amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of these novel compounds, pharmaceutical compositions comprising such compounds and especially the use of such compounds as inhibitors of renin.
摘要翻译： 本发明涉及新的哌啶羧酸酰胺衍生物及其在制备药物组合物中作为活性成分的用途。 本发明还涉及相关方面，包括制备这些新化合物的方法，包含此类化合物的药物组合物，特别是这类化合物作为肾素抑制剂的用途。
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公开(公告)号：EP1981847A1
公开(公告)日：2008-10-22
申请号：EP07705752.9
申请日：2007-01-31
发明人： BEZENCON, Olivier , BUR, Daniel , CORMINBOEUF, Olivier , DUBE, Daniel , GRISOSTOMI, Corinna , MACDONALD, Dwight , MCKAY, Dan , POWELL, David , REMEN, Lubos , RICHARD-BILDSTEIN, Sylvia , SCHEIGETZ, John , THERIEN, Michel , WELLER, Thomas
IPC分类号： C07D211/70 , C07D451/02 , C07D471/08 , A61K31/439 , A61K31/4418 , A61P9/00 , C07D401/14 , C07D413/10 , C07D413/14 , C07D211/34
CPC分类号： C07D211/78 , C07D211/34 , C07D211/70 , C07D401/14 , C07D413/10 , C07D413/12 , C07D413/14 , C07D451/02 , C07D471/08
摘要： The invention relates to novel secondary amine derivatives of formula (I) and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
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