公开(公告)号：EP1981847A1

公开(公告)日：2008-10-22

申请号：EP07705752.9

申请日：2007-01-31

申请人： Actelion Pharmaceuticals Ltd.

发明人： BEZENCON, Olivier ,  BUR, Daniel ,  CORMINBOEUF, Olivier ,  DUBE, Daniel ,  GRISOSTOMI, Corinna ,  MACDONALD, Dwight ,  MCKAY, Dan ,  POWELL, David ,  REMEN, Lubos ,  RICHARD-BILDSTEIN, Sylvia ,  SCHEIGETZ, John ,  THERIEN, Michel ,  WELLER, Thomas

IPC分类号： C07D211/70 ,  C07D451/02 ,  C07D471/08 ,  A61K31/439 ,  A61K31/4418 ,  A61P9/00 ,  C07D401/14 ,  C07D413/10 ,  C07D413/14 ,  C07D211/34

CPC分类号： C07D211/78 ,  C07D211/34 ,  C07D211/70 ,  C07D401/14 ,  C07D413/10 ,  C07D413/12 ,  C07D413/14 ,  C07D451/02 ,  C07D471/08

摘要： The invention relates to novel secondary amine derivatives of formula (I) and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.