专利检索 ap:("Adherex Technologies, Inc.") AND inv:"DOHERTY, Patrick" 第 1 页

1.

发明公开
COMPOUNDS AND METHODS FOR MODULATING CADHERIN-MEDIATED FUNCTIONS 审中-公开
标题翻译：化合物和方法调制函数的CADHERINVERMITTELTEN

公开(公告)号：EP1097168A2

公开(公告)日：2001-05-09

申请号：EP99928963.0

申请日：1999-07-12

申请人： Adherex Technologies, Inc.

发明人： DOHERTY, Patrick , BLASCHUK, Orest, W. , GOUR, Barbara, J.

IPC分类号： C07K14/705 , C07K7/06 , C07K7/64 , A61K47/48 , G01N33/68

CPC分类号： C07K7/06 , A61K38/12 , C07K7/64 , C07K14/705

摘要： Modulating agents and methods for enhancing or inhibiting cadherin-mediated functions are provided. The modulating agents comprise at least an HAV binding motif, an analogue or peptidomimetic thereof, or an antibody or fragment thereof that specifically binds to such a motif. Modulating agents may additionally comprise one or more cell adhesion recognition sequences recognized by cadherins and/or other adhesion molecules. Such modulating agents may, but need not, be linked to a targeting agent, drug and/or support material.