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公开(公告)号：EP1539757A1
公开(公告)日：2005-06-15
申请号：EP03788209.9
申请日：2003-08-13
申请人： AstraZeneca AB
IPC分类号： C07D471/04 , A61K31/437 , A61K31/506 , A61K31/496 , A61P11/06 , A61P37/08
CPC分类号： C07D471/04 , A61K31/437 , A61K31/445 , A61K31/496 , A61K31/506
摘要： There are provided novel compounds of formula (I) wherein R1, R2 and R3 are as defined in the specification and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the kinase Itk.
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公开(公告)号：EP1539758A1
公开(公告)日：2005-06-15
申请号：EP03788212.3
申请日：2003-08-13
申请人： AstraZeneca AB
IPC分类号： C07D471/04 , A61K31/437 , A61K31/445 , A61K31/496 , A61P11/06 , A61P37/08
CPC分类号： C07D471/04 , A61K31/437 , A61K31/445 , A61K31/496 , A61K31/506
摘要： There are provided novel compounds of formula (I) wherein R1, R2 and R3 are as defined in the specification and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the kinase Itk.
摘要翻译： 提供了式（I）的新化合物，其中R 1，R 2和R 3如说明书中所定义;及其药学上可接受的盐; 以及它们的制备方法，含有它们的组合物以及它们在治疗中的用途。 这些化合物是激酶Itk的抑制剂。
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3.发明公开NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES 审中-公开新DIAZASPIROALKANE和它们在疾病治疗的介导CCR8
公开(公告)号：EP1926730A1
公开(公告)日：2008-06-04
申请号：EP06784143.7
申请日：2006-09-04
申请人： AstraZeneca AB
发明人： BÖRJESSON, Lena , CONNOLLY, Stephen , JOHANSSON, Henrik , KRISTOFFERSSON, Anna , LINNANEN, Tero , SHAMOVSKY, Igor , SKRINJAR, Marco
IPC分类号： C07D471/10 , A61K31/407 , A61K31/438 , A61P11/00 , A61P11/06 , C07D487/10
CPC分类号： C07D487/10 , C07D471/10
摘要： The invention provides compounds of general formula (I) wherein A, B, p, w, x, y, and z are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
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