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1.发明授权Use of omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors 有权ω-羧基芳基取代的二苯基脲的用作Raf激酶抑制剂
公开(公告)号：EP1690853B1
公开(公告)日：2010-03-10
申请号：EP05028442.1
申请日：2000-01-12
申请人： Bayer HealthCare LLC
发明人： Riedl, Bernd , Dumas, Jacques , Khire, Uday , Lowinger, Timothy, B. , Scott, William, J. , Smith, Roger, A. , Wood, Jill, E. , Monahan, Mary-Katherine , Natero, Reina , Renick, Joel , Sibley, Robert, N.
IPC分类号： C07D211/78 , C07D211/72 , A61K31/33 , A61K31/54 , A61K31/535 , A61K31/17 , C07C275/20 , C07C275/22 , C07C275/24 , C07C275/28
CPC分类号： C07D295/192 , A61K31/17 , A61K31/18 , A61K31/24 , A61K31/341 , A61K31/40 , A61K31/4035 , A61K31/44 , A61K31/4439 , A61K31/4453 , A61K31/495 , A61K31/496 , A61K31/5375 , A61K31/5377 , C07C275/28 , C07C275/30 , C07C275/32 , C07C275/36 , C07C275/40 , C07C311/29 , C07C317/22 , C07D209/46 , C07D209/48 , C07D209/50 , C07D213/75 , C07D213/80 , C07D213/81 , C07D295/073 , C07D295/12 , C07D295/13 , C07D295/135 , C07D295/18 , C07D401/12 , C07F7/1852 , C07F7/1856
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2.发明授权w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors 有权ω-carboxyarylsubstituierte二苯基脲作为p38激酶抑制剂
公开(公告)号：EP2298311B1
公开(公告)日：2012-05-09
申请号：EP10180762.6
申请日：2000-01-13
申请人： Bayer HealthCare LLC
发明人： Riedl, Bernd , Dumas, Jacques , Khire, Uday , Lowinger, Timothy B. , Scott, William J. , Smith, Roger A. , Wood, Jill E. , Monahan, Mary-Katherine , Natero, Reina , Renick, Joel , Sibley, Robert N.
IPC分类号： A61K31/535 , A61K31/50 , A61K31/445 , A61K31/44 , A61K31/40 , A61K31/34 , A61K31/17
CPC分类号： A61K31/5377 , A61K31/17 , A61K31/18 , A61K31/24 , A61K31/341 , A61K31/40 , A61K31/4035 , A61K31/44 , A61K31/4439 , A61K31/4453 , A61K31/495 , A61K31/496 , A61K31/535 , A61K31/5375 , Y02A50/401 , Y02A50/411 , Y02A50/414 , Y02A50/473
摘要： This invention relates to the use of a group of aryl ureas in treating p38 mediated diseases, and pharmaceutical compositions for use in such therapy.
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3.发明公开Heteroaryl ureas containing nitrogen hetero-atoms as P38 kinase inhibitors 审中-公开Stickstoff Atom enthaltenden Heteroaryl-Harnstoffe als Inhibitoren der P38-Kinase
公开(公告)号：EP2386545A1
公开(公告)日：2011-11-16
申请号：EP11170364.1
申请日：2002-04-17
申请人： Bayer Healthcare LLC
发明人： Dumas, Jacques , Riedl, Bernd , Khire, Uday , Sibley, Robert, N. , Hatoum-Mokdad, Holia , Monahan, Mary-Katherine , Gunn, David, E. , Lowinger, Timothy, B. , Scott, William , Smith, Roger, A. , Wood, Jill, E.
IPC分类号： C07D213/75 , C07D217/22 , C07D401/12 , C07D215/38 , C07D403/12 , A61K31/44 , A61K31/47 , A61P29/00
CPC分类号： C07D213/75 , A61K31/17 , A61K31/18 , A61K31/24 , A61K31/341 , A61K31/40 , A61K31/4035 , A61K31/44 , A61K31/4439 , A61K31/4453 , A61K31/47 , A61K31/4709 , A61K31/4725 , A61K31/495 , A61K31/496 , A61K31/5375 , A61K31/5377 , C07D215/38 , C07D217/22 , C07D401/12 , Y02A50/401 , Y02A50/411 , Y02A50/414 , Y02A50/473
摘要： This invention relates to the use of a group of heteroaryl ureas containing nitrogen in treating p38 mediated diseases, and pharmaceutical compositions for use in such therapy.
摘要翻译： 本发明涉及一组含氮的杂芳基脲在治疗p38介导的疾病中的用途，以及用于这种治疗的药物组合物。
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4.发明公开w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors 有权ω-羧基芳基取代基 - 二苯基-Harnstoffe als p38-激酶
公开(公告)号：EP2298311A1
公开(公告)日：2011-03-23
申请号：EP10180762.6
申请日：2000-01-13
申请人： Bayer Healthcare Llc
发明人： Riedl, Bernd , Dumas, Jacques , Khire, Uday , Lowinger, Timothy B. , Scott, William J. , Smith, Roger A. , Wood, Jill E. , Monahan, Mary-Katherine , Natero, Reina , Renick, Joel , Sibley, Robert N.
IPC分类号： A61K31/535 , A61K31/50 , A61K31/445 , A61K31/44 , A61K31/40 , A61K31/34 , A61K31/17
CPC分类号： A61K31/5377 , A61K31/17 , A61K31/18 , A61K31/24 , A61K31/341 , A61K31/40 , A61K31/4035 , A61K31/44 , A61K31/4439 , A61K31/4453 , A61K31/495 , A61K31/496 , A61K31/535 , A61K31/5375 , Y02A50/401 , Y02A50/411 , Y02A50/414 , Y02A50/473
摘要： This invention relates to the use of a group of aryl ureas in treating p38 mediated diseases, and pharmaceutical compositions for use in such therapy.
摘要翻译： 本发明涉及一组芳基脲在治疗p38介导的疾病中的用途，以及用于这种治疗的药物组合物。
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