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公开(公告)号:EP3356373A1
公开(公告)日:2018-08-08
申请号:EP16770510.2
申请日:2016-09-26
发明人: LÜCKING, Ulrich , GEISLER, Jens , HOG, Daniel , SCHOLZ, Arne , PETERSEN, Kirstin , LIENAU, Philip , STEGMANN, Christian , ANDRES, Dorothee , ZHENG, Kunzeng , GAO, Ping , CHEN, Gang , XI, Jiajun , HERBERT, Simon Anthony , SIEMEISTER, Gerhard , WERBECK, Nicolas
IPC分类号: C07D498/04 , A61K31/4375 , A61K31/519 , C07D498/14 , A61P35/00 , A61P31/00 , A61P9/00
摘要: The present invention relates to novel macrocyclic sulfondiimine compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).
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公开(公告)号:EP3359544A1
公开(公告)日:2018-08-15
申请号:EP16774683.3
申请日:2016-09-30
发明人: LÜCKING, Ulrich , HOG, Daniel , GEISLER, Jens , SCHOLZ, Arne , PETERSEN, Kirstin , LIENAU, Philip , STEGMANN, Christian , ANDRES, Dorothee , SIEMEISTER, Gerhard , WERBECK, Nicolas
IPC分类号: C07D498/08 , C07D498/18 , C07D515/08 , A61K31/529 , A61P35/00
摘要: The present invention relates to novel modified macrocyclic compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).
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公开(公告)号:EP3359544B1
公开(公告)日:2020-08-12
申请号:EP16774683.3
申请日:2016-09-30
发明人: LÜCKING, Ulrich , HOG, Daniel , GEISLER, Jens , SCHOLZ, Arne , PETERSEN, Kirstin , LIENAU, Philip , STEGMANN, Christian , ANDRES, Dorothee , SIEMEISTER, Gerhard , WERBECK, Nicolas
IPC分类号: C07D498/08 , C07D498/18 , C07D515/08 , A61K31/529 , A61P35/00
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公开(公告)号:EP3356373B1
公开(公告)日:2020-02-19
申请号:EP16770510.2
申请日:2016-09-26
发明人: LÜCKING, Ulrich , GEISLER, Jens , HOG, Daniel , SCHOLZ, Arne , PETERSEN, Kirstin , LIENAU, Philip , STEGMANN, Christian , ANDRES, Dorothee , ZHENG, Kunzeng , GAO, Ping , CHEN, Gang , XI, Jiajun , HERBERT, Simon Anthony , SIEMEISTER, Gerhard , WERBECK, Nicolas
IPC分类号: C07D498/04 , A61K31/4375 , A61K31/519 , C07D498/14 , A61P35/00 , A61P31/00 , A61P9/00
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公开(公告)号:EP3601253A1
公开(公告)日:2020-02-05
申请号:EP18712899.6
申请日:2018-03-22
发明人: LÜCKING, Ulrich , HOG, Daniel , CHRIST, Clara , SACK, Ulrike , SIEGEL, Franziska , LIENAU, Philip , WERBECK, Nicolas
IPC分类号: C07D401/12 , C07D239/30 , C07D498/04 , A61K31/519 , A61P9/00 , A61P35/00
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公开(公告)号:EP3601236A1
公开(公告)日:2020-02-05
申请号:EP18712892.1
申请日:2018-03-22
发明人: LÜCKING, Ulrich , HOG, Daniel , CHRIST, Clara , SACK, Ulrike , SIEGEL, Franziska , LIENAU, Philip , WERBECK, Nicolas
IPC分类号: C07D239/30 , C07D498/08 , C07D498/18 , C07D213/61 , A61K31/519 , A61P35/00 , A61P9/00
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