-
公开(公告)号：EP3359544A1
公开(公告)日：2018-08-15
申请号：EP16774683.3
申请日：2016-09-30
发明人： LÜCKING, Ulrich , HOG, Daniel , GEISLER, Jens , SCHOLZ, Arne , PETERSEN, Kirstin , LIENAU, Philip , STEGMANN, Christian , ANDRES, Dorothee , SIEMEISTER, Gerhard , WERBECK, Nicolas
IPC分类号： C07D498/08 , C07D498/18 , C07D515/08 , A61K31/529 , A61P35/00
摘要： The present invention relates to novel modified macrocyclic compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).
-
公开(公告)号：EP3710456A1
公开(公告)日：2020-09-23
申请号：EP18810918.5
申请日：2018-11-15
发明人： FURST, Laura , SERRANO-WU, Michael, H. , LEMKE, Chris , MCKINNEY, David , FITZGERALD, Mark , NASVESCHUK, Christopher , LAZARSKI, Kiel , FERRARA, Steven, James , WEI, Guo , MCCARREN, Patrick, Ryan , THEDE, Kai , MENGEL, Anne , CHRIST, Clara , KUHNKE, Joachim , JOHANNES, Sarah, Anna, Liesa , BUCHGRABER, Philipp , KLAR, Ulrich , SACK, Ulrike , KAULFUSS, Stefan , FERNANDEZ-MONTALVAN, Amaury, Ernesto , WERBECK, Nicolas , MÖNNING, Ursula , NOWAK-REPPEL, Katrin
IPC分类号： C07D513/22 , A61P35/00 , A61K31/5377
-
公开(公告)号：EP3710450A1
公开(公告)日：2020-09-23
申请号：EP18811160.3
申请日：2018-11-15
发明人： THEDE, Kai , MENGEL, Anne , CHRIST, Clara , KUHNKE, Joachim , JOHANNES, Sarah, Anna, Liesa , BUCHGRABER, Philipp , KLAR, Ulrich , SACK, Ulrike , KAULFUSS, Stefan , FERNANDEZ-MONTALVAN, Amaury, Ernesto , WERBECK, Nicolas , MÖNNING, Ursula , NOWAK-REPPEL, Katrin , MORTIER, Jeremie, Xavier , MCCARREN, Patrick, Ryan , SERRANO-WU, Michael, H. , LEMKE, Chris , MCKINNEY, David , FITZGERALD, Mark , NASVESCHUK, Christopher , LAZARSKI, Kiel , FERRARA, Steven, James , FURST, Laura , WEI, Guo , HARVEY, Rebecca, Ann , PAYNE, Daniel , PESNOT, Thomas , WILSON, Craig
IPC分类号： C07D487/14 , C07D487/04 , C07D498/04 , C07D498/14 , C07D498/20 , A61P35/00 , A61K31/4162
-
4.发明公开
公开(公告)号：EP3710449A1
公开(公告)日：2020-09-23
申请号：EP18810917.7
申请日：2018-11-15
发明人： FERRARA, Steven, James , SERRANO-WU, Michael H. , LEMKE, Chris , MCKINNEY, David , FITZGERALD, Mark , NASVESCHUK, Christopher , LAZARSKI, Kiel , FURST, Laura , WEI, Guo , MCCARREN, Patrick, Ryan , THEDE, Kai , MENGEL, Anne , CHRIST, Clara , KUHNKE, Joachim , JOHANNES, Sarah, Anna, Liesa , BUCHGRABER, Philipp , KLAR, Ulrich , SACK, Ulrike , KAULFUSS, Stefan , FERNANDEZ-MONTALVAN, Amaury, Ernesto , WERBECK, Nicolas , MÖNNING, Ursula
IPC分类号： C07D487/14 , C07D403/04 , C07D498/14 , A61P35/00 , A61K31/4162
-
公开(公告)号：EP3356373A1
公开(公告)日：2018-08-08
申请号：EP16770510.2
申请日：2016-09-26
发明人： LÜCKING, Ulrich , GEISLER, Jens , HOG, Daniel , SCHOLZ, Arne , PETERSEN, Kirstin , LIENAU, Philip , STEGMANN, Christian , ANDRES, Dorothee , ZHENG, Kunzeng , GAO, Ping , CHEN, Gang , XI, Jiajun , HERBERT, Simon Anthony , SIEMEISTER, Gerhard , WERBECK, Nicolas
IPC分类号： C07D498/04 , A61K31/4375 , A61K31/519 , C07D498/14 , A61P35/00 , A61P31/00 , A61P9/00
摘要： The present invention relates to novel macrocyclic sulfondiimine compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).
-
公开(公告)号：EP3710447A1
公开(公告)日：2020-09-23
申请号：EP18807574.1
申请日：2018-11-15
发明人： THEDE, Kai , MENGEL, Anne , CHRIST, Clara , KUHNKE, Joachim , JOHANNES, Sarah, Anna, Liesa , BUCHGRABER, Philipp , KLAR, Ulrich , SACK, Ulrike , KAULFUSS, Stefan , FERNANDEZ-MONTALVAN, Amaury, Ernesto , WERBECK, Nicolas , MÖNNING, Ursula , FERRARA, Steven, James , SERRANO-WU, Michael, H. , LEMKE, Chris , MCKINNEY, David , FITZGERALD, Mark , NASVESCHUK, Christopher , LAZARSKI, Kiel , FURST, Laura , WEI, Guo , MACCARREN, Patrick, Ryan , HARVEY, Rebecca, Ann , WILSON, Craig
IPC分类号： C07D487/14 , C07D487/04 , C07D498/04 , C07D498/14 , C07D498/20 , A61P35/00 , A61K31/4162
-
公开(公告)号：EP3359544B1
公开(公告)日：2020-08-12
申请号：EP16774683.3
申请日：2016-09-30
发明人： LÜCKING, Ulrich , HOG, Daniel , GEISLER, Jens , SCHOLZ, Arne , PETERSEN, Kirstin , LIENAU, Philip , STEGMANN, Christian , ANDRES, Dorothee , SIEMEISTER, Gerhard , WERBECK, Nicolas
IPC分类号： C07D498/08 , C07D498/18 , C07D515/08 , A61K31/529 , A61P35/00
-
公开(公告)号：EP3458459A1
公开(公告)日：2019-03-27
申请号：EP17734982.6
申请日：2017-05-17
发明人： JOHANNES, Sarah Anna Liesa , BUCHGRABER, Philipp , KLAR, Ulrich , CHRIST, Clara , FERNANDEZ-MONTALVAN, Amaury, Ernesto , MÖWES, Manfred , LIENAU, Philipp , EIS, Knut , SACK, Ulrike , MÖNNING, Ursula , SCHOLZ, Arne , KUHNKE, Joachim , THEDE, Kai , WERBECK, Nicolas , SERRANO-WU, Michael H. , LEMKE, Chris , MCKINNEY, David , FITZGERALD, Mark , NASVESCHUK, Christopher , LAZARSKI, Kiel , FERRARA, Steven, James , FURST, Laura , WEI, Guo , MCCARREN, Patrick, Ryan
IPC分类号： C07D487/14 , C07D487/04 , C07D498/04 , C07D498/14 , C07D498/20 , A61K31/4162 , A61P35/00
-
公开(公告)号：EP4065584A1
公开(公告)日：2022-10-05
申请号：EP20808437.6
申请日：2020-11-24
发明人： SCHMEES, Norbert , WORTMANN, Lars , KIRCHHOFF, Dennis , NGUYEN, Thi, Thanh, Uyen , WERBECK, Nicolas , BÖMER, Ulf , PETERSEN, Kirstin , KOBER, Christina , STÖCKIGT, Detlef , LECHNER, Christian , OFFRINGA, Rienk
IPC分类号： C07D487/10 , A61K31/4375 , A61P9/00 , A61P31/12 , A61P35/00
-
公开(公告)号：EP4065574A1
公开(公告)日：2022-10-05
申请号：EP20808438.4
申请日：2020-11-24
发明人： SCHMEES, Norbert , WORTMANN, Lars , KIRCHHOFF, Dennis , NGUYEN, Thi, Thanh, Uyen , WERBECK, Nicolas , BÖMER, Ulf , PETERSEN, Kirstin , KOBER, Christina , STÖCKIGT, Detlef , LECHNER, Christian , MEIER, Robin, Michael , HERBERT, Simon, Anthony , KERSCHGENS, Isabel, Patrizia , KOSEMUND, Dirk , OFFRINGA, Rienk , GREES, Mareike
IPC分类号： C07D403/04 , A61K31/4353 , A61P35/00
-
-
-
-
-
-
-
-
-
搜索结果
16 条记录 (耗时 0.014 秒)
